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Biomedical subjects

R L Steinbrook

Publications and source records attributed to R L Steinbrook.

3 recordsLinked to original sources

Voluntary screening for human immunodeficiency virus (HIV) infection. Weighing the benefits and harms.

Voluntary screening for human immunodeficiency virus (HIV) infection may help prevent the spread of the HIV epidemic if persons who test positive alter behaviors that may transmit infection. Protecting persons from unknowingly being exposed to HIV infection must be balanced against respecting the autonomy of individuals being screened. Seropositive patients may feel a stigma and be subjected to discrimination if confidentiality of test results is breached. In patients without high-risk behaviors, the positive predictive value of HIV testing may be substantially increased if tests are done in reference laboratories and if further confirmatory tests are run on a second blood specimen. For persons with high-risk behaviors, HIV testing can be recommended to those who want to reduce uncertainty about their HIV status or whose medical care would change if they were seropositive. Health care workers can maximize benefits of screening and minimize harm by educating and counseling patients before HIV testing, discussing the confidentiality of HIV test results, urging patients to disclose positive test results to sex partners, and advising patients on how to reduce high-risk behaviors.

Acquired Immunodeficiency Syndrome↗

Kidneys for transplantation.

A profound kidney shortage compromises the effective care of renal failure patients in the United States and other nations. This article discusses the need for kidneys, the procurement of live donor and cadaver organs, and strategies to increase organ donation. It suggests that the kidney shortage can be minimized and perhaps eliminated through the use of living related donors whenever appropriate, and through more efficient procurement of volunteered cadaver kidneys. Two other strategies to increase the supply of kidneys-the sale of organs and "contracting out" laws-are rejected. The first is unacceptable in the Western world. The second is fraught with constitutional and ethical problems, and may not lead to more kidney procurement.

Cadaver↗