DIFFERENTIAL EFFECT OF CYTOTOXIC ISOANTIBODY ON BENIGN AND MALIGNANT CELLS IN HUMAN SEROUS FLUIDS. A PRELIMINARY STUDY.
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Biomedical subjects
Publications and source records attributed to R L WALFORD.
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Serums obtained from paired humans following reciprocal fourthset skin homografts, or from a prolonged series of reciprocal intradermalinjections of leukocytes, displayed potent cytotoxic activity againstlymphocytes of certain individuals and no activity against lymphocytes of other persons. Study of one family suggested that lymphocyte reactivity may be transmitted according to simple Mendelian genetics. Itis probable that this reactivity reflects and can be used to identifyspecific histocompatibility antigens in man.
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