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Biomedical subjects

R Lázaro Santander

Publications and source records attributed to R Lázaro Santander.

11 recordsLinked to original sources
PubMed2002

[Subcutaneous nodules in children: subcutaneous granuloma annulare].

Subcutaneous granuloma annulare is a benign, chronic inflammatory lesion located usually at scalp or extremities and typical of childhood. Its etiology is unknown and no link with systemic diseases has been found. A thorough clinical history and normality at complementary tests are enough for its identification. It tends to dissaparition, so no therapy is needed although histologic study will let a definitive diagnosis. A case in a three years-old boy is reported. He was submitted because of four asymptomatic, long-lasting tough lesions at his scalp, without other antecedents. Radiologic and hematologic tests found no alteration. Two months later a larger size was appreciated in one of them, so it was removed and its histology was diagnostic for granuloma annulare. After a 10 months follow-up, no change in size has been detected in the remaining ones.

Child, Preschool↗
PubMed2001

[Low-grade oncocytic adrenal carcinoma].

OBJECTIVE: To report a case of left adrenocortical neoplasm. METHODS: A case of left adrenocortical neoplasm measuring 16 x 10 x 7 cm in a 47-year-old male is presented. After puncture biopsy, a left adrenalectomy through the abdominal approach was performed. RESULTS: Immunohistochemical studies showed reactivity to the anti-Melan-A A103 antibody, suggesting an adrenal origin of the tumor cells. Strong reactivity to the mES-13 mitochondrial antibody, which is characteristic of oncocytes, made ultrastructural studies unnecessary. CONCLUSIONS: In this type of tumor, an increased mitotic activity and necrosis are suggestive of malignancy. Despite the foregoing, most of this type of lesions are clinically benign and nonfunctioning.

Adenocarcinoma↗
PubMed1999

[Intravesical hemangiopericytoma].

OBJECTIVE: To report on a case of hemangiopericytoma of the urinary bladder mimicking a urothelial tumor. METHODS: A case of hemangiopericytoma arising from the urinary bladder in a 78-year-old man is described. The initial symptoms included gross hematuria, and it was confused with a urothelial tumor. The difficulty in making the diagnosis in regard to the site of origin and histological findings are discussed. The literature is briefly reviewed. RESULTS/CONCLUSIONS: Ultrasound and urographic evaluation showed an intravesical mass which was suspected to be a urothelial tumor. The patient was submitted to transurethral surgery. Histological analysis and immunohistochemical techniques demonstrated a hemangiopericytoma.

Aged↗
PubMed1998

[Bladder malacoplakia: apropos of 2 cases].

OBJECTIVES: To describe two cases of malakoplakia of the bladder with an unusual form of presentation and review the cases previously reported in the literature. METHODS/RESULTS: Two patients, a 61-year-old female and a 71-year-old male, are described. Both patients had a history of recurrent infection caused by coliform pathogens. Treatment consisted of trimethoprim sulfamethoxazole, ascorbic acid and bethanecol chloride, together with extended TUR of the bladder lesion. CONCLUSIONS: Although malacoplakia of the bladder is considered to be a benign disease, close follow-up is warranted due to frequent recurrence of symptoms and the difficulty in achieving long-lasting effects since it is frequently associated with immunosuppression.

Aged↗
PubMed1994

[Adrenal epithelial cyst of embryonal vestiges].

A 10 x 6.5 cm cyst with ciliated cell lining was removed from a 43-year-old woman. The immunohistochemical studies demonstrated that the cyst cells expressed keratins (Lu 5+) and the adrenal cortical cells did not, suggesting that the cyst lining was not derived from adrenal cells. The presence of ciliated cells indicates that the cyst was derived from embryonal vestiges.

Adrenal Gland Diseases↗
PubMed1993

[Solitary metachronous pancreatic metastasis of renal adenocarcinoma].

We report the case of a patient who underwent a left nephrectomy for clear cell adenocarcinoma. Four years later he presented with jaundice due to a single metastasis of the same tumour in the head of the pancreas which was resected. The favourable prognosis with surgery encourages a radical approach.

Adenocarcinoma↗
PubMedDate not supplied

[Sarcomatoid carcinoma of the larynx].

Sarcomatoid carcinoma of the upper aerodigestive tract is an unusual neoplasm with differential cellular differentiation. Microscopically, sarcomatoid carcinomas have an element of squamous-cell carcinoma and a pleomorphic sarcoma-like component, which may simulate granulation tissue, malignant fibrous histiocytoma, osteosarcoma, or malignant giant-cell tumor of soft tissues.

Aged↗
PubMedDate not supplied

[Renal angiomyolipoma in childhood: a clinical case].

The renal angiomyolipomas are unusual benign tumors which more than 50 per cent, are associated with tuberous sclerosis or intestinal linphangiomatosis. They can be discovered in a radiologic study by chance or to be associated with flank and abdominal pain and hematuria. The ultrasonographic imagen is characteristic and its management is conservative.

Child↗