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Biomedical subjects

R Lachman

Publications and source records attributed to R Lachman.

At least 19 recordsLinked to original sources

[Professional and personal characteristics of Israeli public hospital physicians].

The profile of the Israeli public hospital physician was evaluated in a survey of 703 physicians. Background variables (age, sex, marital status), working habits (time devoted to various activities, management position) professional characteristics (specialty, seniority, tenure, etc.) and hospital characteristics (size, ownership) were recorded. The profile that emerged was that of physicians in their early 40's, the majority men, 2/3 senior physicians, and half with tenure. They work 50 to 60 hours a week, mostly in clinical work, with less than 10% of their time in research. Physician mobility between hospitals is low: in any 5-year period very few positions become available, and then usually only when physicians retire. For these openings there is severe competition by a large number of residents. It is clear that research in hospitals should be encouraged in order to maintain hospital standards.

Adult

Intravenous erythromycin for postpyloric intubation.

Of 100 consecutive patients referred for antroduodenal manometry, we successfully intubated 89 with endoscopic and/or fluoroscopic guidance. In 8 of 8 patients who had failed with our usual techniques, we infused erythromycin 3 mg/kg i.v. over 1 h, and the tube moved through the pylorus and into the duodenum. Erythromycin, which stimulates propagation of 3 high amplitude antral contractions/min, appears to be a safe, noninvasive means to facilitate the postpyloric passage of tubes.

Adolescent

The determination of bone age in the elbow as compared to the hand. A study in 390 children.

In a prospective study, bone age (BA) from both hand and elbow was assessed in 390 children, aged 6-15 years, in order to determine: (a) whether or not BA assessment from the hand and from the elbow give comparable results, and (b) whether the accuracy of predicting skeletal age from the hand may be improved by the additional BA determination in the elbow. BA assessment in the hand was performed according to the method of Greulich and Pyle while the standards of Schinz and Baensch were used for the elbow. Statistical analysis of data was carried out according to age groups as well as according to groups of clinical diagnoses. With only one exception in the group of so-called "healthy individuals", there was no difference between "hand age" and "elbow age". Thus, except in a very small group of subjects, both methods of BA assessment were found to be equivalent in predicting skeletal age in children between 6-15 years. Equivocal results were obtained regarding the question of whether the accuracy of BA assessment in the hand may be improved by the simultaneous BA determination from the elbow. Until further studies on larger statistical material provide more conclusive information in this matter, we feel that the combined determination of BA in the hand and elbow is not warranted for clinical purposes.

Adolescent

Neonatal dwarfism.

We have not attempted to discuss the many forms of dwarfism with onset in childhood or adolescence, nor has it been possible to examine the many other causes of the small for gestational age infant, recently the subject of a review in this series. The evaluation of a child with a skeletal dysplasia requires a multidisciplinary approach utilizing clinical, genetic, radiographic, and morphologic findings. Because of the marked heterogeneity of this group of disorders, genetic and prognostic counseling should not be given until the physician is confident that he has made a definitive diagnosis.

Bone Diseases, Developmental

Yersinia colitis.

A 2-year-old child with a febrile, non-bloody diarrheal illness of acute onset with repeatedly negative stool and blood cultures for pathogenic bacteria is presented. Sigmoidoscopic and roentgenographic studies revealed an inflammatory colitis. Unfortunately, diagnostic perserverance and a high index of suspicion resulted in a positive stool culture for Yersinia enterocolitica. Serologic study and clinical course provided data consistent with the diagnosis of an infectious colitis due to Yersinia enterocolitica. This case demonstrates the necessity to consider Yersinia enterocolitica in the radiographic differential diagnosis of Crohn's disease of the colon or ulcerative colitis, as well as intractable diarrhea of childhood.

Biopsy

Heterogeneity in the campomelic syndromes. Long-and short-bone varieties.

Analysis of 9 cases of bilateral bent limbs (campomelia) and dwarfism, as well as a review of the literature, indicate that campomelic syndrome appears to be a well-defined distinct disorder which the authors call long-limbed campomelic syndrome. Other neonates with congenital bent-limbed dwarfism can be classified as having short-limbed campomelic syndrome, and among these at least two distinct forms have been delineated--the craniosynostotic and the normocephalic form. Congenital bent bones also occur in a variety of generalized disorders of ossification that must be distinguished from these well-defined types of campomelic dwarfism.

Abnormalities, Multiple