PubMed Health⌕ Search

Biomedical subjects

R Lalloni

Publications and source records attributed to R Lalloni.

12 recordsLinked to original sources

[Relationship of P 50 in normal subjects in physiological condition and their percentage of Hb-CO].

After a short review on the actual knowledge about the relationship between P50 of human blood in normal adults and newborns and their relative amount of Hb-CO, the Authors analyze a wide series of subjects in Whom the survey has been performed at the physiological saturations of Hb-CO. The results show that, a part from an usually high percentage of Hb-CO of still unknown origin in the newborn, the P50 of normal adults and newborns appear to be relatively stable and not shifted towards the right in spite of the progressive increasing of hypoxia induced by still physiological levels of Hb-CO.

Adolescent↗

[Preliminary study on P50 and on other parameters correlated with hemoglobin function in normal subjects chosen at random].

In a wide survey on normal non-selected healthy adults, the Authors have found normal pHs in venous blood, a P50 slightly shifted to the left, in comparison with the mean values reported in other series for males and females, normal Hb amounts, normal 2,3-DPG levels, normal met-hemoglobin values and increased rates of Hb-CO. All these data and the possible relationship among them are discussed, with particular reference towards P50 and Hb-CO, which appears to be mainly raised, even if not only, in smokers people. At this regard the Authors hypothetize that if the four hemes of hemoglobin are fully saturated with CO, a right shifted oxy-hemoglobin dissociation curve of variable extent will be observed, whereas, if the hemes are not fully saturated, the curve could be shifted, more or less, towards the left. These two conditions could be coexisting in an unstable, non-enzymatic equilibrium, which could modify by itself the usual sigmoid shape (and the P50 values) of the whole blood oxygen affinity.

2,3-Diphosphoglycerate↗

[A case of melanoderma erroneously considered to be addisonian].

A case characterized by a dark pigmentation of the skin with an initial hypotension and a lung tuberculosis in the remote anamnesis is described. The skin pigment was formed by lipofuscin and emosiderin, but only the former was found in the liver biopsy. Anyway, the pigment was not melanine and the surrenalic function of the patient was completely normal; therefore, an Addisonism syndrome is excluded. The patient was treated for a very long time with DOCA: this caused hypertension, probably supported by the hypervolemia triggered by the DOCA depending retenction of sodium and water. A sure diagnosis of the case was not made, but an Addisonism syndrome was certainly excluded.

Addison Disease↗

[Association of liver cirrhosis, hepatoma, extensive aortic thrombosis and chronic duodenal peptic ulcer in the same patient].

An association of alcoholic cirrhosis of the liver, hepatoma, extensive aortic thrombosis, and chronic bleeding peptic ulcer of the duodenal bulbus in a patient who survived only three days after hospitalisation is reported. An explanation of each disease is given and the fact that a basically hypocoagulative situation (cirrhosis) can give rise to thrombosis of the aorta is stressed. Production and release into the circulation of thromboplastins by the hepatoma (paraneoplastic syndrome), leading aortic atherosclerosis and slow circulation due to haemorrhagic cardiocirculatory collapse was the most likely explanation.

Aged↗

[Non-endocarditic mitral insufficiency].

A case of non endocarditic mitral insufficiency in a 76 years old woman is described. After an extensive pathogenetical introduction, a comparison is made between clinical features of this case an its pathogenetical possibilities. The conclusion is drawn that there are most probabilities for an atherosclerosis of the antero-medial limbus of the mitral valve, arising from a coexisting atherosclerotic mild stenosis of the aortic valves.

Aged↗

[Chronic obstructive lung diseases and arterial hypertension].

800 clinical cards of patients whose discharge diagnosis was chronic bronchopathy and essential hypertension have been examined retrospectively. After appropriate statistical calculations, it has been found that the association is not casual either in men or women below the age of 60. In such cases the Student T test gives a result of less than 0.001. The possible pathogenetic mechanisms for this association are discussed in the light of the literature of recent year.

Age Factors↗

[Clinico-radiological considerations on senile atrophic gastritis].

59 cases of patients in geriatric age have been examined in which clinical symptomatology, radiographic exams and laboratory data had indicated the possible presence of gastric neoplasia. The repetition of the radiographic exam after giving methoclopramide for some days has demonstrated, excluding neoplastic lesion, that it was senile atrophic pseudo-tumoral gastritis. The diagnosis has been confirmed in numerous cases by gastroscopy with biopsy.

Age Factors↗