PubMed Health⌕ Search

Biomedical subjects

R Litt

Publications and source records attributed to R Litt.

At least 37 records · Page 2Linked to original sources

Hyponatremia in a neonate of a cocaine abusing mother.

Neonatal hyponatremia can be caused by increased sodium losses, inadequate sodium intake, increased maternal or neonatal water load or by water retention secondary to excess of ADH release. Cocaine use by pregnant women has not as yet been reported to correlate with hyponatremia in the newborn infant. We present a case of an infant whose mother used cocaine regularly during the last stages of pregnancy and who developed hyponatremia in the first week of life. A mechanism is proposed and discussed.

Adult↗

[Comparative study of a series of normal knees and a series of knees with patellar instability].

In studying the long-term follow-up of 39 cases of patellofemoral instability operated in our department for recurrent dislocation, we also analyzed their morphological appearance on X-ray. We compared the data given by Maldague and Malghem, Dejour and Walch for the pathological conditions of our cases with the same number of normal knees. This comparative analysis showed that measuring the bulging of the upper part of the trochlea and the depth of its groove on a lateral view is a reliable method to evaluate patellar instability. The classical axial view gives less useful information to quantify the instability. However, this axial view shows a particular aspect in the cases of severe instability: the fulcrum of the trochlea is displaced inwards while the inner trochlear facet is smaller or even absent. This precise radiological examination and the complete clinical examination with an analysis of the "morphotype" (Lerat) are necessary in the screening, diagnosis and treatment of severe patellofemoral instability.

Follow-Up Studies↗

[Treatment of major patellar instability. Results of the Fèvre-Dupuis operation].

In the treatment of recurrent subluxation and dislocation of the patella in adolescents and young adults, the authors describe a method consisting of: --a modified Roux procedure for internal transposition and advancement of the anterior tibial tuberosity; --the Lecène technic for over-the-top reinsertion of the vastus medialis on the lateral aspect of the patella. All the patients had a plaster cast for 10 days followed by rehabilitation until normal knee function was achieved. Stiff knees were mobilized under general anesthesia. Normal activity was progressively resumed 6 weeks after surgery. Out of the 31 patients (41 knees) available for objective follow-up evaluation, 26 were women and 5 men, with an average age of 19 years. The mean follow-up period was 9 and a half years with a minimum of 2 years and a maximum of 23. End results in terms of relief of pain, patellar stability and knee function were gratifying. Thirty knees were rated good, 8 fair and 3 poor. No recurrence of subluxation or dislocation was found.

Adolescent↗

[Pathology of the anterior peroneus tendon and that of the intermetatarsal bone].

The inconstant peroneus tertius is the fourth muscle in the antero-lateral aspect of the leg. Its tendon crosses the fourth tendon of the extensor hallucis brevis on the dorsal aspect of the cuboïdo-metatarsal joint. If an impingement occurs it may provoke a painful condition and a typical synovial cyst. The anatomy and the pathology of the condition are described. The treatment is very simple: the inconstant tendon should be removed when it produces symptoms. An accessory bone, the intermetatarsal bone, located at the proximal part of the first intermetatarsal or intercuneiform space, may have various shapes. It can provoke pain in the first space when pressure is exerted on capsulo-ligamentous structures or on neuro-vascular elements. The treatment is excision of the accessory bone.

Foot Diseases↗

Sweet syndrome in early childhood.

A 21-month-old child with acute febrile dermatosis, leukocytosis and skin biopsy showing intradermal neutrophil infiltrate was diagnosed as suffering from Sweet syndrome. This syndrome is rare in children, described heretofore in only seven paediatric patients. The clinical and histological features, differential diagnosis, as well as the potential association with more widespread systemic diseases are discussed.

Biopsy↗

The familial ovarian cancer registry: progress report.

BACKGROUND: Ovarian cancer can be cured if detected early enough, but usually has already metastasized when diagnosed. A family history of ovarian cancer is still the strongest known risk factor. OBJECTIVE: To identify women at risk for ovarian cancer and design a program of surveillance. METHODS: Prospective registry of women with a family history of ovarian cancer. RESULT: From April 1991 to July 1993, 137 women (119 families), mean age 43, registered with the Familial Ovarian Cancer Registry. The 119 pedigrees revealed 171 cases of ovarian cancer. Only one family is undocumented by pathology. Forty of 137 registrants have more than one relative with ovarian cancer. Six percent of pelvic examinations were abnormal for potential adnexal disease. In 4% of registrants, initial CA125 concentrations were abnormal. Ultrasound examinations were abnormal in ovarian size (5%), in morphology (3%), and by resistive indices (4%). Four ultrasounds were repeated earlier than routine. Using "standard" fees, the total cost to diagnose the one case of ovarian cancer discovered was $68,848. CONCLUSIONS: This approach still cannot be considered cost-effective. We are continuing to search for genetic and molecular markers of disease in women at greatest risk and in their affected relatives.

Adult↗