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Biomedical subjects

R Lochan

Publications and source records attributed to R Lochan.

13 recordsLinked to original sources

Renal dysfunction in enteric fever.

Twenty-five culture positive cases of enteric fever were studied to see the effect of the disease on various kidney functions. The parameters studied were urine examination, blood urea, serum creatinine, serum electrolytes, 24 hours urinary examination (proteins, creatinine, electrolytes), creatinine clearance rate, plain X-ray abdomen, intravenous urogram and circulating immune complexes. Fifteen patients with fever of non-specific origin served as controls. Renal dysfunction was observed in four patients (16%). Repeat tests showed that abnormalities of renal functions, though significant, were short lasting and reversible. Renal biopsy done in three of these cases did not reveal any abnormality.

Acute Kidney Injury

Percutaneous transluminal balloon angioplasty of the aorta in patients with aortitis.

Four patients with aortitis and stenotic lesions of the aorta were successfully treated by percutaneous transluminal balloon angioplasty. The peak systolic gradient across the constrictions decreased from 82.5 +/- 35.7 to 37.5 +/- 18.5 mm Hg immediately after dilatation. Repeat angiography in the first three patients performed 2 months later showed a further decrease in the gradient to 13.8 +/- 9.5 mm Hg. There were no complications during or after the procedure, and all the patients have shown remarkable symptomatic relief during the follow-up.

Adolescent