PubMed Health⌕ Search

Biomedical subjects

R Lockwood

Publications and source records attributed to R Lockwood.

26 records · Page 2Linked to original sources
PubMed1967

Metachromatic leukodystrophy (sulfatide lipidoses) cultured in vitro.

Cerebral white matter from a patient with metachromatic leukodystrophly was successfully cultured in vitro. A luxuriant growth in Rose chambers and in roller tubes was apparent by the 14th day. The outgrown cells contained large numbers of granules which stained dark brown with cresyl violetacetic acid. The growth and metachromasia were maintained up to 80 days in vitro.

Adolescent↗
PubMedDate not supplied

Attacks by packs of dogs involving predation on human beings.

Dog bites are a medical problem for millions of people, children being the most common victims. Human deaths attributable to dog bite injury (not rabies) are relatively infrequent. There have been some epidemiologic reviews, but this study is the first attempt to arrive at an understanding of bites involving predation on human beings by conducting behavioral examinations under controlled conditions of the dogs involved, and by interviewing victims, witnesses, and people familiar with the animals.The three cases studied involved two fatalities and an attack that was nearly fatal. The victims were 11, 14, and 81. In each case, owned pet dogs consumed some human tissue. The severity of the victims' injuries was not the consequence of a single dog bite, but the result of repeated attacks by dogs behaving as a social group. Factors that might contribute to a dog's regarding human beings as potential prey were examined, including hunger, prior predation, group behaviors, defense of territory, previous interactions with people, the presence of estrous female dogs, and environmental stimuli. In two of the cases, it was possible, by using similar stimuli, to duplicate the circumstances at the time of the attack.The results of the observations showed the value of behavioral analysis and simulations methods in evaluating possible factors in dog attacks.Among the many factors probably involved in severe dog attacks are the size, number, and nutritional status of the dogs; the dogs' previous aggressive contacts with people; the victim's age, size, health, and behavior; and the absence of other human beings in the vicinity.

Adolescent↗
PubMedDate not supplied

The ecology of dog bite injury in St. Louis, Missouri.

A detailed analysis of all the reported dog bites that occurred over a 2-year period in St. Louis, Mo., provided new insight not only into the severity of the problem, but also the environmental context for injury. Dog bite is a major medical problem that affects at least 1 of every 222 people and specifically 1 of every 83 children, 5 to 9 years old. Nearly 20 percent of all the children bitten were injured on the head or face, a source of concren and expense for all concerned. Nearly 10 percent of all bites were classified as serious. In only 25 percent of all injuries did the victim's behabior involve the dog at the time ofe victim interacting with the dog's owner. The victim was on the dog owner's property in about u9 percent of the incidents, and in about 48 percent of the cases the bite took pla-e near the owner's property. Bite incidents go up whenever the weather is conductive to street activity. More than 85 percent of all the biting dogs had owners. These results indicate that society's views of dog bite injury, which tend to minimize the problem and find fault with the victim, must be re-evaluated. It is time to place less emphasis on the victim and even the animal and review thae public health implications of dog ownership

Adolescent↗