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Biomedical subjects

R Logan

Publications and source records attributed to R Logan.

At least 55 records · Page 3Linked to original sources
PubMed1983

Clinical and biochemical findings in Leber's hereditary optic atrophy.

Clinical findings in Leber's hereditary optic atrophy (LHOA) are reviewed and the results given of treatment with a regimen based on the hypothesis that the disease is a manifestation of cyanide toxicity. Recent biochemical investigations confirm disturbed cyanide metabolism and suggest that zinc deficiency may be implicated.

Adolescent↗
PubMed1982

Effect of heparin on plasma free fatty acid concentrations after acute myocardial infarction.

Free fatty acid concentrations in plasma measured after in vivo heparinisation are often overestimated because of ex vivo lipolysis of variable degrees. A new method has been developed using immediate extraction of blood which obviates this and shows that the true rise in plasma free fatty acid concentration after heparin in ambulant ward patients and in patients with acute myocardial infarction is less than previously reported. The small rise in plasma free fatty acid concentration after heparin is unlikely to have adverse metabolic effects in most patients during acute myocardial infarction.

Adult↗
PubMed1981

A multi-disciplinary coronary rehabilitation programme: three years initial experience.

We have established a multi-disciplinary cardiac rehabilitation programme for patients with a variety of cardiac problems. The majority are post-myocardial infarction patients who attend the programme from the time of their early mobilisation on the ward until the end of their convalescence. In this paper we describe the programme and the way in which we have attempted an initial assessment of its impact on the psychosocial and medical status of patients one year after infarction. The results of this assessment do not, on the whole, support our strong impression of the value of such treatment. The reasons for this apparent discrepancy will be discussed.

Adult↗
PubMed1981

Pre-discharge exercise testing involving weight carrying after myocardial infarction.

Exercise testing involving weight carrying was undertaken on 36 consecutive men under the age of 70 years at a mean of 12.2 days after myocardial infarction before their discharge from hospital. The test consisted of four stages: walking for 3 minutes at 5.3 km/h, carrying a 13.6 kg weight for 3 min at a speed of 4.4 km/h, holding a 22.7 kg weight with the arm flexed for 1 min and carrying the 22.7 kg weight for 1 min at a speed of 2.6 km/h. Twenty-four (66 percent) men completed all four stages during which mean maximal heart rate and systolic blood pressure were 143/min and 166 mmHg respectively. No test was discontinued because of arrhythmias and complex ventricular arrhythmias occurred in only one man. On subsequent maximal treadmill testing on 32 of these subjects at a mean of 7.2 weeks post-infarction, significantly more of those completing the pre-discharge test achieved an average work capacity for their age. As a result of this study, we believe that exercise testing of this type involving weight carrying can be helpful in the management of patients convalescing after myocardial infarction.

Adult↗
PubMed1979

Serum cholecystokinin, basal acid secretion, and infantile pyloric stenosis.

The fasting serum cholecystokinin-like activity was measured in 21 infants with pyloric stenosis and in 13 normal controls. No significant difference was found between the two groups. The basal acid secretion was measured by continuously aspirating the previously emptied stomach for one hour. The basal gastric volume and the total and the free acidity were all greater in the pyloric group.

Cholecystokinin↗
PubMed1977

Drug-induced extrapyramidal signs in chronic liver disease--a case report.

Extrapyramidal effects of phenothiazines and related compounds are well documented and may be dose related. Impaired drug metabolism can occur in chronic liver disease. A case is reported of extra pyramidal signs occurring in a patient with alcoholic liver disease given the antiemetic Ancoloxin in therapeutic dosage.

Basal Ganglia Diseases↗