PubMed Health⌕ Search

Biomedical subjects

R Lukin

Publications and source records attributed to R Lukin.

13 recordsLinked to original sources

Lumbar disc disease and stenosis.

In recent years MR has been the major advancement in the imaging of lumbar disc disease. Its advantages include multiplanar imaging, excellent resolution, and absence of ionizing radiation. Although CT remains an efficient and accurate method of evaluating the spine, we currently recommend MR imaging as the best initial examination. Myelography with follow-up CT scans should be reserved for specific patients in whom additional information is needed after MR images or CT scans.

Humans↗

Enlargement of cerebral third ventricle in psychotic patients with delayed response to neuroleptics.

Enlargement of the cerebral third ventricle appears to be a replicable finding in groups of patients with psychotic illnesses, and there is evidence for an association of third ventricle enlargement with poorer response to treatment. Third ventricle area and width were measured from computed tomography (CT) scans in 24 mood-incongruent psychotic patients and 14 controls age and gender matched to schizophrenic patients. Patients were treated with a fixed dose of haloperidol and classified as rapid responders (55% symptom reduction on New Haven Schizophrenic Index (NHSI) within 4.5 +/- 1.3 days) or delayed responders (55% symptom reduction on NHSI within 18.6 +/- 10.5 days). The significant enlargement of third ventricle area was isolated among the 12 delayed neuroleptic responders (19.3 +/- 9.0 mm2) compared with the 14 controls (11.7 +/- 4.8 mm2, p = 0.01), and 12 other mood-incongruent psychotics. Third ventricle width also showed a trend towards larger width in the delayed responders. There was a clear positive correlation between ventricular size and patient's age exclusively in the delayed responders (r = 0.78); a comparable relationship between ventricular size and age was not present in controls, or in the other psychotics. This finding is consistent with an age-related progressive degenerative process in the central nervous system (CNS) isolated to the neuroleptic-delayed responsive psychotics.

Adult↗

Magnetic resonance imaging and computerized tomography scanning of herpes simplex encephalitis. Report of two cases.

The authors present two cases of herpes simplex encephalitis (HSE) in which computerized tomography (CT) scanning and magnetic resonance imaging (MRI) were performed. They also review the literature on the use of these imaging modalities in cases of HSE. The striking changes noted in these cases on T2-weighted magnetic resonance images in comparison to the CT findings suggest that MRI will help speed recognition of nonhemorrhagic HSE abnormalities.

Adult↗

Spontaneous cerebellar hematoma associated with chronic cerebellar stimulation. Case report.

A 24-year-old man developed a spontaneous cerebellar hematoma 5 years after the implantation of cerebellar electrodes. No vascular malformations were found either intraoperatively or radiographically. The histopathological findings of the cerebellar tissue obtained at biopsy from the region surrounding the electrodes support the hypothesis of a causal relationship between the spontaneous cerebellar hemorrhage and chronic cerebellar stimulation.

Adult↗