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Biomedical subjects

R Lundén

Publications and source records attributed to R Lundén.

13 recordsLinked to original sources
PubMed1982

Effect of EACA, PAMBA, AMCA and AMBOCA on fibrinolysis induced by streptokinase, urokinase and tissue activator.

A study is presented in which the inhibiting effects of eACA, PAMBA, AMCA and AMBOCA on fibrinolysis induced by three activators have been compared by a clot lysis method. The order of inhibitory potency was AMBOCA greater than AMCA greater than PAMBA greater than EACA. The activity ratios obtained were found to be influenced by the level of inhibition. At low levels of inhibition the differences between the inhibitory activities are usually more pronounced than at high levels. The degree of inhibition is dependent on the fibrinolytic activator used. The order of sensitivity to the inhibitors was, within the analytical conditions used, found to be: tissue activator greater than streptokinase greater than urokinase. The results are discussed in comparison to the different activity ratios reported by others.

4-Aminobenzoic Acid↗
PubMed1980

Separation of herpes simplex virus virions and nucleocapsids on Percoll gradients.

Herpes simplex virus (HSV) virions and nucleocapsids were separated and purified by centrifugation in density gradient of polyvinylpyrrolidone-coated colloidal silica (Percoll). Virions and nucleocapsids banded at densities of 1.07 and 1.03 g/ml, respectively. The distribution in the gradient of virions and nucleocapsids suggested that particles were discriminated according to difference in size rather than in density. The reduction of cell proteins in preparations of purified virions was 1300--2100 times. The recovery of infective virus was approximately 30%.

Animals↗