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R M Abellera

Publications and source records attributed to R M Abellera.

10 recordsLinked to original sources
PubMed1989

Tenosynovial lipochondromatosis of the flexor hallucis, common toe flexor, and posterior tibial tendons.

Presented is a case report of a girl with a lipomatous lesion of the medial ankle with chondromatous transformation of the sheath of the common and great tow flexor tendons. The lesion was completely excised. Histologic examination confirmed the diagnosis of tenosynovial lipochondromatosis of the involved tendons. The patient was symptom free at the 18-month follow-up examination.

Ankle Joint↗
PubMed1984

Hürthle cell tumors of the thyroid gland. A clinicopathologic review and long-term follow-up.

We reviewed the pathology and clinical follow-up of 26 patients with H urthle cell adenomas and three patients harboring H urthle cell carcinomas, who were treated at our medical center from 1950 to 1979. Although benign lesions could not be distinguished from malignant tumors by cytologic features alone, other pathologic features allowed differentiation. A total thyroidectomy was performed in only one patient; the remaining patients were treated by less extensive operations. None of the patients with benign adenomas, including those with tumors greater than 2 cm in diameter, experienced recurrent or metastatic disease. The period of observation varied from two to 22 years (mean, 8.5 +/- 7.7 years). We conclude that lobectomy is a satisfactory operation for removal of benign H urthle cell tumors, and reserve total or near-total thyroidectomy for cases displaying pathologic evidence of malignancy.

Adenoma↗
PubMed1978

Cure of acromegaly by operative removal of an islet cell tumor of the pancreas.

We studied a 30 year old woman in whom acromegaly was cured by operative removal of a large cystic beta cell adenoma of the pancreas. We detected substantial amounts of immunoreactive human growth hormone (hGH)-like activity in a tumor tissue extract. Extracts of the tumor and a normal human pituitary gland eluted from a Sephadex G-75 column in two identical peaks. Serial dilutions of the tumor extract displaced radioactive 125I hGH parallel to a standard curve. Surprisingly, an extract of a normal human pancreas contained large amounts of hGH-like activity and gave results similar to those of the tumor extract on gel chromatography and on serial dilution displacement in the growth hormone immunoassay. Paper electrophoretic studies of 125I hGH after incubation with normal pancreatic and tumor extracts with and without enzyme inhibitors suggested that pancreatic proteolytic enzymes damaged the 125I hGH used in growth hormone radioimmunoassay and produced a false detection of hGH.

Acromegaly↗