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R M Bergström

Publications and source records attributed to R M Bergström.

At least 19 recordsLinked to original sources

Overstimulation, occipital/somesthetic cerebral cortical depth, and cortical asymmetry in mice.

It was hypothesized on theoretical grounds that sensory multidimensional overstimulation (stress) during development might not yield increased cerebral cortical depth, as has been found for enriched rearing conditions. We found that such overstimuliation in growing mice resulted in a low occipital/somesthetic cortical depth ratio in comparison to EC-stimulated mice (EC, enriched conditions). It is unclear whether this is due to small occipital or large somesthetic cortical depth. Principal-component analytic techniques indicate a complicated interaction during development involving sex, environmental condition, and cortical asymmetry.

Animals↗

Electrical activity of neurons cultured in vivo.

A method is presented, where glass microchambers (1 X 2 mm) are implanted in various brain regions of 4-10 days old rats. The microchamber contains a collagen coated coverglass with cell material taken from the same region of a littermate. Investigation of the neural growth occurs after 4-14 days, on an inverted phase contrast microscope in a temperature and pH controlled, oxygenated BSS medium. Various growth geometries of neurons are observed and microelectrode recordings reveal spontaneous and electrically evoked spike and complex activity.

Animals↗