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R M Burian

Publications and source records attributed to R M Burian.

15 recordsLinked to original sources
PubMed2000

On the internal dynamics of Mendelian genetics.

This paper offers a revisionist account of the development of Mendelian genetics, focusing on the 'problem of the gene', 1900-1930. I examine conflicting claims about the composition, location, and action of genes posed by Bateson, the Morgan group, and Goldschmidt. Their research programs focused on different phenotypes and were based on different assumptions about the nature of genes. The problem of the gene transcended such specific research programs, but their findings had to be taken into account to solve it. The need to resolve conflicting claims drove Mendelian geneticists to exploit the resources and invade the turf of other disciplines in their search for a sound characterization of the gene. The problem of reconciling conflicting views greatly influenced the development of genetics and provided the stimulus for many of the discoveries made by geneticists from 1900 to 1940.

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PubMed2000

France in the era of Mendelism (1900-1930).

This paper describes and explains the reception of Mendelism among French biologists at the beginning of the 20th Century. Three dimensions of description must be taken into account: scholarly diffusion; transmission of the new science through teaching and textbooks; and effective research. These three axes of description do not provide the same picture: Mendelian research was widely reported among specialists; no significant teaching of Mendelism took place in the years 1900-1930; by 1930 only one biologist, Lucien Cuénot, had carried out significant genetic research, but he abandoned his Mendelian research in 1914. The resistance to Mendelism can be attributed to four categories of factors, none of which is sufficient. The first category includes a series of intellectual factors: a massively positivist conception of science, an approach to heredity that privileged a 'physiological' theory, and a poor development of cytology. The second set of factors stems from the failure of French academic biologists to establish a strong interaction with plant and animal breeding. The third factor is the relatively weak influence of the eugenic ideology in France. Finally, the particular organization of French universities, together with the deaths of numerous young scientists during World War I, amplified the effects of the previous factors.

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PubMed1999

The French school of genetics: from physiological and population genetics to regulatory molecular genetics.

French genetics had unusual beginnings. There are clear indications that the French biological establishment resisted Mendelian genetics strenuously from about 1910 to 1940. From about 1930 to 1950 several unconventional research programs with a strongly physiological orientation paved the way for the full entrance of French biology into genetics after World War II. This review examines some salient features of this history to clarify the strengths, weaknesses, and distinctive features of French genetics until about 1965. We suggest that after that data French genetics slowly merged into the international mainstream as genetics has become a largely molecular discipline.

Animals↗