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Biomedical subjects

R M Coles

Publications and source records attributed to R M Coles.

7 recordsLinked to original sources

HM Dockyard, Devonport: 1947 mortality study.

To investigate the effect of occupational exposure to asbestos on mortality, names of all 6292 men born on or after 1 January 1910 and employed as industrial workers in the RN Dockyard, Devonport on 1 January 1947 were submitted to the Office of Population Censuses and Surveys for tracing. Follow-up continued until the end of 1978: over 99% were traced; 3% emigrated; and there were 1043 (17%) deaths. On the basis of the mortality in England and Wales for each five years of age and each five calendar years, the standardized mortality ratio (SMR) was 96. Adjusting the rates for the lower mortality in south-west England, the SMR was 104. No relation was found between SMR and date of birth, and there was only a very slight excess among those more heavily exposed to asbestos. Thirty-one men died with mesothelioma and a further 14 with asbestosis or pulmonary fibrosis. The circulatory disease death rate was slightly raised (SMR = 118), but no more than might have been expected for manual workers. Asbestos-related deaths accounted for at least 4% of all deaths, but probably not many more.

Aged

Chronic leukaemia.

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Antineoplastic Agents

Mesothelioma risks in a naval dockyard.

There have been 108 deaths from mesothelioma of the pleura or peritoneum in Plymouth and the immediate neighborhood as of mid-1978. Ninety-six deaths have been associated with work at the Devonport Dockyard, 53 of which represented men employed at the dockyard in 1966. Occupational mesothelioma rates were similar to those recorded in London asbestos textile workers. Above average rates in this study were observed in laggers, boilermakers, painters, welders and burners, and shipwrights. In addition to mesothelioma in other men with neighborhood exposure at work, cases have occurred in men whose only exposure has been to the environment within the walls of the dockyard, outside ships and workshops where asbestos has been handled. No case has been seen in indoor office workers. There is no evidence of any increase in risk to the population of Plymouth outside the dockyard.

Adolescent