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Biomedical subjects

R M Doran

Publications and source records attributed to R M Doran.

7 recordsLinked to original sources

Microsporidial keratoconjunctivitis in a patient with AIDS.

A male patient is described with acquired immune deficiency syndrome (AIDS) who developed chronic keratoconjunctivitis and chronic sinusitis due to infection with the microsporidian Encephalitozoon cuniculi. Diagnosis was confirmed by electron microscopic examination of conjunctival epithelial cells and nasal polypectomy specimens. Treatment with propamidine isethionate 0.1% (Brolene) eye drops six times daily led to a prompt resolution of the keratoconjunctivitis.

Acquired Immunodeficiency Syndrome

Preferential looking in the mentally handicapped.

We have assessed the feasibility of Preferential Looking (PL), using Teller Acuity Cards, for the estimation of binocular and monocular visual acuities in a group of mentally handicapped adults. Our results show the comparison between grating and recognition acuities, inter-observer variation, success rate, time taken and the sensitivity of this method in identifying monocular visual deficit in this group of subjects. The reasons for success or failure with PL methods in relation to criteria for mental handicap are discussed.

Adult

Preferential looking in clinical practice: a year's experience.

Preferential Looking (PL) is now a well established laboratory method of measuring visual acuity in preverbal children. We have evaluated the feasibility of its routine use in clinical practice. We present our methods and results obtained in 80 normal children and 36 children with visual disorder and discuss the problems encountered in applying this test.

Aging

The use of computerized contrast sensitivity, Arden gratings and low contrast letter charts in the assessment of amblyopia.

Contrast sensitivity measured with an electronic display was compared with Arden gratings and low contrast letter charts in normal and amblyopic children and adults. The low contrast letter charts and the Arden gratings used in the conventional manner revealed no additional information over that obtained by conventional Snellen acuity. However, the interocular differences found with each plate of the Arden gratings compared favourably with the computerized CSF. With the addition of an extra plate to test at a higher spatial frequency, the Arden gratings would be a useful technique for monitoring amblyopia therapy.

Adult

Assessment of vision in amblyopia.

This paper presents a brief review of clinical methods of assessment of vision in amblyopic infants and children. The problems encountered in this context include attention and motivation of the patient, and reliability and standardisation of method. Various solutions are examined and the relevance of the newer techniques of acuity estimation by preferential looking (PL), visual evoked cortical potentials (VECP) and psychophysical tests of contrast sensitivity is discussed.

Amblyopia