Biomedical subjects
Publications and source records attributed to R M Fasanella.
These results in a small group of patients seem quite clear for the benefit of cyproheptadine in patients with BEB, especially where botulinum A injections fail, are too expensive, or are refused. The apparent memory improvement requires further study. A search for more effective serotonin antagonists without the anticholinergic and antihistaminic side effects of cyproheptadine is needed and is in process.
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An historical review up to 1952 of surgical methods intended to change the refractive power of the eye is given. Experimental work at Yale utilizing 49 rabbits and dogs includes repeated prior studies done by others. This work incorporated: 1. Procedures on the anterior surface of the cornea, 2. Procedures on the posterior surface of the cornea, and 3. Procedures through all corneal layers (total segmented corneal resection) (SCR). In obtaining desired refractive changes, SCR created relatively higher refractive changes, assured stability and a more accurate calibration and calculation in advance of surgical procedures, however, even though total segmented corneal resection seemed superior, it was often complicated in animals.
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