Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere.
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Biomedical subjects
Publications and source records attributed to R M Heintz.
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Continued experience confirms the suitability of electrovitreotomy for dividing pathogenically taut proliferative and non-proliferative vitreous forms with a minimum of bleeding, and an inability to cut vitreous of ordinary consistency and tension. It differs directly with electrovitrectomy in these regards. To use effectively with a minimum of complications it is mandatory to have a vitrectomy capability immediately at hand and to respect a wide variety of interrelated factors that include: current density, electrical resistance of tissues, duration of electrical action: dimension, insulation, and configuration of the electrode: configuration, tension, location, and morphological content of dissectable structures. Mobile and dispersed blood in the liquid of the retrovitreal space often surrounds cuttable vitreous lesions. Frequently rest causes it to sediment and improves viewing sufficiently to permit effective electrovitreotomy without vitrectomy.
This is a description of an alternative type of vitrectomy instrument system which is characterized by specific advantages for mobilizing and removing sluggish intracapsular lens material, blood, debris, or plasmoid liquid pooled or sedimented at the posterior pole; and modular one-surgeon units adaptable to contemporary vitrectomy devices and techniques with a minimum of surgical or instrument modification. Electrovitreotomy for relaxing fixed folds due to taut opaque vasoproliferative bands inaccessible to or extremely hazardous with other cutting methods is a complementary procedure of value.
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