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Biomedical subjects

R M Jager

Publications and source records attributed to R M Jager.

11 recordsLinked to original sources
PubMed1979

Umbilical metastasis as the presenting symptom of cecal carcinoma.

Umbilical metastases were encountered as the initial presentation of cecal adenocarcinoma in a 62-year-old woman. Intravenous infusion of 5-fluorouracil, along with intralesional injections of 10% 5-fluorouracil, resulted in regression of the tumor masses on the abdominal wall. Although umbilical metastasis is rare, its significance in diagnosing an otherwise silent colorectal cancer warrants the physician's awareness.

Adenocarcinoma, Mucinous↗
PubMed1978

Contact spot xeromammography in the early diagnosis of breast cancer.

As currently used, xeromammography is a sensitive and specific test to detect early breast cancers. However small the incidence of false positive and false negative diagnoses may be, they do lead to either false assurance of health in some breast cancer patients or cause some cancer-free women to undergo further radiologic and/or surgical diagnostic workup. To improve the accuracy of xeromammography in breast cancer diagnosis, contact spot xeromammography was used to enhance the image detail when findings on the conventional xeromammogram proved ambiguous. This contact spot technique has now been used about 2,500 times in 10,000 asymptomatic women. Our experience with contact spot xeromamography is described, including instances in which it led to correct diagnoses.

Breast Neoplasms↗
PubMed1977

Single view negative mode xeromammography: an approach to reduce radiation exposure in breast cancer screening.

With the increasing use of xeromammography in mass screening for breast cancer, the potential risk to women from repeated exposure to low energy ionizing radiation must be weighed against the benefit of early detection of breast cancer. Although xeromammography allows detection of 80-90% of breast cancers before metastases occur, the radiation hazard from repeated xeromammographic screening must be considered and attempts made to reduce radiation exposure. The dose from xeromammography can be reduced by greater than one half with the single mediolateral view, negative mode imaging technique. Moreover, no reduction of diagnostic accuracy of xeromammography in early detection of breast cancer was found with this technique.

Breast Neoplasms↗
PubMedDate not supplied

Granulocyte transfusions for patients with severe thermal burns.

Ten severely burned (greater than 50% BSA) pediatric and young adult patients developed 19 episodes of clinical sepsis of four or more days duration. During eight of the 19 septic episodes the patients received granulocyte transfusions (median, four; range, two to seven). Risk variables, types and prevalence of infections, mainly Pseudomonas aeruginosa and antibiotic regimens were similar for all the septic episodes studied. All eight episodes (100%) resolved in the transfused group while eight of 11 (72%) episodes resolved in the nontransfused group. Patients survived four episodes of ecthyma gangrenosum when granulocyte transfusions were used and the single episode in which they were not used was fatal. Granulocyte transfusions may be helpful in severely burned patients with sepsis.

Blood Transfusion↗