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Biomedical subjects

R M McCully

Publications and source records attributed to R M McCully.

At least 19 recordsLinked to original sources
PubMed1983

Lymphosarcoma in a cat.

Feline leukaemia virus (FeLV) antigen was detected in a cat from Cape Town which was subjected to euthanasia after a long history of upper respiratory infection and progressive emaciation. Based on the necropsy findings and subsequent histopathological examinations, a diagnosis of lymphosarcoma was made. It is regarded as likely that this tumour was caused by infection with FeLV.

Animals↗
PubMed1979

Canine pneumocystis pneumonia.

This is a case report of pneumocytosis of an eight month old Dachschund from the Cape Province. Clinically it was an afebrile disease with signs limited primarily to the lower respiratory tract. The report consists of a short history, the histopathologic findings, evidence of the electron microscopic confirmation of the diagnosis and a brief discussion. It is believed to represent the first case of canine pneumocystosis in the Republic of South Africa.

Animals↗
PubMed1978

Observations on the pathology of canine microsporidiosis.

The available literature on canine microsporidiosis indicates that this disease, primarily of young dogs, is a distinct clinicopathological entity. It has been confused with canine distemper and rabies, and must be differentiated from toxoplasmosis. Information available on the spectrum of pathological change associated with this disease is incomplete but a distinct pattern emerges from a study of the reports. The aetiological agent appears to have a predilection for the central nervous system and kidneys, but other tissues and organs, and especially the liver, may also be infected. Vasculitis and perivasculitis, which may include fibrinoid necrosis, seem to be a basic lesion. Cellular inflammation ranges from polymorphonuclear leukocyte infiltration in areas of necrosis to focal granulomas. There may be no cellular reaction to compact groups of organisms. Histopathological and ultrastructural studies of this case augment our knowledge of the pathological changes seen with canine microsporidiosis.

Animals↗
PubMed1975

Observations on naturally acquired hepatozoonosis of wild carnivores and dogs in the Republic of South Africa.

Hepatozoonosis was studied in hyaenas, lions, jackals, cheetahs and one leopard in the Kruger National Park and compared with the condition seen in dogs in the Republic of South Africa. Hepatozoon schizonts were found in the wild carnivores. The genesis of microschizonts was followed and is illustrated. The schizonts were sometimes very plentiful in the lung, myocardium and skeletal muscle, and were also encountered in the spleen, liver and lymph nodes. Gametocytes were present in leucocytes. The host response was usually very mild. sporogenous development in ticks was observed in Rhipicephalus simus females removed from an infected hyaena and R. sanguinelus adults fed on an infected jackal in the nymphal stage. Attempts to transmit Hepatozoon from a jackal to dogs by means of ticks gave inconclusive results.

Animals↗