Selection and use of mass reference standards.
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Mass Spectrometry↗
Biomedical subjects
R M Milberg
Publications and source records attributed to R M Milberg.
Appendix 2. Reference ions for exact mass measurements.
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Amino Acid Sequence↗
Minicomputer-based multichannel signal averager for acquisition of weak and transient mass spectra.
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Computers↗
Cardiac toxicity of perchloroethylene (a dry cleaning agent).
Perchloroethylene analysis was performed on plasma of a 24-year-old white man who presented with a history of premature ventricular beats, dizziness, and headaches. There was no clinical, electrocardiographic, radiologic, or echocardiographic evidence of heart disease. The occurrence of premature ventricular beats and the patient's symptoms were more pronounced when the plasma level of perchloroethylene was high (3.8 ppm). Removal of exposure to perchloroethylene relieved the patient's symptoms and the premature beats completely disappeared.
Adult↗
A reproducible gas chromatographic mass spectrometric assay for low levels of methylphenidate and ritalinic acid in blood and urine.
A rapid, sensitive method of analysis for methylphenidate and ritalinic acid in blood and urine has been developed using gas chromatography mass spectrometry and selected ion monitoring for separation and detection. The methylphenidate is isolated by solvent extraction into chloroform and the ritalinic acid is isolated by salting out into isopropyl alcohol, followed by methylation and subsequent solvent extraction. The method has been applied to the study of methylphenidate metabolism and excretion in adults and hyperactive children undergoing treatment with methylphenidate.
Adult↗