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Biomedical subjects

R M Paredes Esteban

Publications and source records attributed to R M Paredes Esteban.

15 recordsLinked to original sources

[Indication of appendectomy in the recurrent abdominal pain].

INTRODUCTION: The frequency of the recurrent abdominal pain without demonstrable pathology is high and in occasions it takes to the surgeon to practice an appendectomy. In most of the cases the pain disappears. This performance although subjective, it doesn't base on objective data, what takes us to carry out this work. MATERIAL AND METHOD: The study is carried out in 47 patients with recurrent abdominal pain and subjected to appendectomy, 17 were excluded by diverse causes. The vermiform appendixes were studied by morphological and immunohistochemical methods, using the monoclonal antibodies, valuing morphologic sing of a chronic inflammation of the appendix. RESULTS: 100% of the samples studied presented microscopically chronic inflammatory changes microscopically. We observe fibrose in 100%, lympho-plasmocytic inflammatory infiltrate in 60% and a lymphocytes T prevalence has more than enough lymphocytes B. CONCLUSIONS: Our results support the existence of a clinical-pathological condition that can be defined as chronic appendicitis and therefore it justifies the appendectomy in recurrent abdominal pain when another disease has been excluded.

Abdominal Pain↗

[Valoration of the FAS in the contralateral testis after unilateral testicular torsion. Experimental study in rats].

The role the FAS and BCL-2 in the apoptosis of testicular cells in the contralateral testis after unilateral testicular torsion, was investigated. We compared with control group. These experiments were performed in male Wistar rats prepuberal old. FAS and BCL-2 determination is realized in cells cultures of contralateral testis. Flow cytometry and immunohistochemistry studies, using a FAS and BCL-2 specific monoclonal antibody, were utilized to value FAS y BCL-2 expression on testiculaires cells following unilateral testicular torsion. We observed an increase of expression of FAS and decrease of BCL-2 in the contralateral testis in comparison with control group. The present results may indicate that the expression of this molecules is implicated in cellular apoptosis.

Animals↗

[Apoptosis in the cryptorchidism. Role of the FAS protein in it's modulation].

The cellular degeneration, present at the criptorchidism leads to a malfunction in the spermatogenosis and it's due to cellular apoptosis (programed cellular death). This process is turned on and modulated by different ways. One of then is mediated by Ag-Ac reactions and a protein called FAS seems to have an important role in it's modulation. We studied the relation between FAS an the increased apoptosis in undescended testics. Testicular biopsies were done in criptorchid patients during orchidopexy and FAS was measured by immune-techniques. Our results seem to dismiss FAS as a modulation apoptosis factor in the cryptorchidism.

Apoptosis↗

[Immunohistochemical study of hypertrophic pyloric stenosis].

INTRODUCTION: In spite of the clinical experience about infantil Hypertrophic Pyloric Stenosis (IHPS), its etiopathology remains unknown. Recent studies have been focussed in immunohistochemistry techniques for valuing the neuronal development in the pyloric muscle. MATERIAL AND METHODS: We took biopsy from 10 babies diagnosed of IHPS and 10 babies with similar age, died because of other causes. Immunohistochemical study was performed using monoclonal antibodies: S100 protein, GFAP, enolasa and neurofilaments NF. The results were showed semi-quantitativement as strong (++), moderate (+) and absent (-). Immunotinction of the myenteric plexus (ganglion cells and satellite) and nervous fibers of the muscle layer, were done. RESULTS: We observed a poor immunoreactivity in the muscle layer (longitudinal and circular) in the 60-70% of specimens of pyloric muscle in babies with IHPS. GFAP were absent in the 80% in the myenteric plexus. This poor innervation may be related to the etiopathogenesis of pyloric stenosis and hypertrophy.

Humans↗

[Treatment of psoas abscess. Report of a case and review of the literature].

Psoas abscess is an infrequent disease. We present a right psoas abscess diagnosed in a thirteen-year-old child. There wasn't a history of known trauma nor immunodeficiency. We didn't find another infection focus so the abscess was described as primary one. This is the most commonly presentation in children. Staphylococcus aureus was the bacteria identified in blood culture. The presenting symptoms were bottom and hip pain, limp and fever. The differential diagnosis was established with suppurative arthritis of the hip. Diagnosis was confirmed by Magnetic Resonance. In regard to treatment the patient was exclusively treated with systemic antibiotics, high spectrum of activity. The patient didn't require percutaneous-drainage. Though surgical drainage wasn't made, evolution was favourable and recurrence wasn't observed.

Adolescent↗

[Progressive acquired lymphangioma: report of a case and review of the literature].

We present 2-year-old patient with a allopecia lesions in scalp, and clinique diagnostic of Cutis Aplasia. The anatomopathologic study have diagnosed the lesions as Acquired Progressive Lymphangioma (APL). Is a rare vascular tumour that has a tendency to appear in childhood an to progress slowly over the years. It could present as a solitary erythematous macule or plaque and a simple excision is usually curative. Our patient is the youngest reported in the literature.

Child, Preschool↗

[Apoptosis of the contralateral testis after unilateral testicular injury. Experimental study].

INTRODUCTION: The results of both clinical and experimental studies suggest that some testicular unilateral lesions cause infertility due to disruption of spermatogenesis. The cellular mechanism responsible for the degenerative changes is still unclear. OBJECTIVE: Study of the cellular viability in the contralateral testis after unilateral testis injuries. MATERIAL AND METHOD: Six groups of 10 prepuberal Wistar rats subjected to unilateral testicular lesion. To identify the cellular death by "apoptosis" in situ, analysis of DNA fragmentation was performed in cytometric flow. RESULTS: The present study demonstrated an increase of the apoptosis in the contralateral testis after unilateral testicular lesion.

Animals↗

[Experimental testicular torsion: its effect on the contralateral testicle].

The purpose of this project is to determine the lesion in contralateral testis after unilateral testicular torsion. For that is reproduced the lesion in an experimental model animal using 35-45 days old Wistar rats. The study of the contralateral testis is performed 30-35 days after lesion, once orchiectomy with histopathological and ultrastructural analysis, was made. We observed zonal tubular atrophy, alteration of spermatogenesis, abnormal formation of spermatozoa and death cellular by apoptosis.

Animals↗

[Duplication of the colon: a case report].

We report a new case of intestinal duplication in a child of two years old with acute abdomen. At the laparotomy was found to be due to tubular duplication ascending colon. A resection duplication joined a tract of normal colon where are was performed, with termino-terminal anastomosis. The postoperative course was excellent.

Abdomen, Acute↗

[Solitary intestinal fibromatosis: an unusual cause of neonatal intestinal obstruction].

We report a new case of solitary intestinal fibromatosis (SIF) in a neonate with intestinal obstruction in the first day of life. At the laparotomy was found to be due to a solid mass in the jejunum. A segmental jejunal resection with anastomosis was performed. Histologic examination showed a SIF. The postoperative course was excellent in contrast to cases of congenital fibromatosis with multiples lesions, which carries a poor prognosis.

Female↗

[Isolated congenital stenoses of the extrahepatic bile ducts].

Congenital isolated strictures of the extrahepatic bile ducts are very rare, with only eleven cases reported until 1990. We report two infants (3 and 2 months old, respectively) one of them with a choledocal stenosis and the other with a congenital stricture of the common hepatic duct and spontaneous perforation of the biliary tract. Dilatation of the distal stricture with insertion of T-tube was performed during surgical act. We get success with this technique in both cases.

Cholestasis, Extrahepatic↗

[Appendicular carcinoid tumor in childhood].

Apendicular Carcinoid tumors are very infrequent, being lower than 0.1% of the appendicectomies carried out. We report on the case of a 13 year-old girl, with Acute Appendicitis picture. The appendix was removed and the histological study revealed the presence of the carcinoid tumor with a diameter of a 6 mm. Where non-invasive treatment was decided on, and at present, after two years follow-up, there has been no recurrence.

Adolescent↗

[Congenital sternal cleft].

We report two congenital sternal cleft cases, Ravitch type 1, and treated in our hospital during a period of five teen years. This is a rare malformation and the experience is poor. Surgical primary close was realized into the first month of life with satisfactory evolution.

Female↗