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Biomedical subjects

R M Perinpanayagam

Publications and source records attributed to R M Perinpanayagam.

At least 19 recordsLinked to original sources
PubMed1996

Seroprevalence of hepatitis B and C virus in two institutions caring for mentally handicapped adults.

Hepatitis B virus infection is common in institutions caring for the mentally handicapped. Hepatitis B virus and hepatitis C virus share routes of transmission but the prevalence of hepatitis C virus infection in this population is unknown. We have tested 101 patients from two institutions in South-East England caring for adults with mental handicap for the presence of hepatitis C antibody, hepatitis B core antibody, and if necessary hepatitis B surface antigen. None tested positive for hepatitis C antibody, but 43 had hepatitis B core antibody of whom 14 were chronic carriers positive for hepatitis B surface antigen. Unlike hepatitis B virus, hepatitis C virus infection appears to be uncommon in UK institutions.

Adult↗
PubMed1992

Streptococcal necrotising fasciitis.

Three cases of streptococcal necrotising fasciitis are described. Its relative rarity and the lack of superficial inflammation leading to diagnostic difficulty is emphasised. The diagnosis is readily confirmed microbiologically but the clinician should bear in mind that antibiotics may not be curative and that surgery is often required.

Aged↗
PubMed1990

Early-onset neonatal pneumococcal sepsis in siblings.

The case of a woman who in two successive pregnancies produced premature infants affected by early-onset Streptococcus pneumoniae type 8 sepsis is described. Low maternal levels of pneumococcal IgG antibodies were demonstrated after the second delivery, and vaccination with 'Pneumovax' produced a rise in antibody levels. Attention is drawn to the similarity between early-onset pneumococcal neonatal sepsis and group B streptococcal sepsis. Mothers of infants affected by early-onset pneumococcal sepsis who have low pneumococcal antibody levels run the risk of subsequent babies being similarly affected and vaccination should be considered to prevent recurrence.

Adult↗
PubMed1981

Haemophilus endocarditis.

Two cases are presented of Haemophilus endocarditis in patients with presumed normal valves. One case was due to H. influenzae presenting as a typical case of infective endocarditis and the other was due to H. para-influenzae presenting as an acute pyrexia of unknown origin. The difficulties in making the diagnosis and the optimal treatment are discussed.

Anti-Bacterial Agents↗
PubMed1976

Bacteroides: an unusual cause of breast abscess.

Three cases of breast abscess from which the non-sporing anaerobe Bacteroides was isolated are described. This organism has apparently not previously been reported as a cause of abscess in a breast without underlying malignancy.

Abscess↗