Biomedical subjects
R M Pruneta
Publications and source records attributed to R M Pruneta.
[2 cases of anaphylaxis from droperidol].
Following two cases of anaphylactoid reactions during anaesthesia, immunoallergological investigations showed up the responsibility of droperidol, which probably acted by way of an anaphylactic mechanism. In both cases, there were no cardiovascular signs, the main clinical symptom being bronchospasm. The exceptional nature of allergic accidents due to neuroleptic drugs, as opposed to extrapyramidal phenomena, must be underlined. However, these reactions should cast doubts on the safety and usefulness of neuroleptanalgesia.
[Fulminant infectious syndrome after post-traumatic splenectomy].
A 49 year old woman presented a very serious infectious state with respiratory failure, on the third postoperative day following splenectomy for a traumatic ruptured spleen. Despite massive antibiotic treatment and treatment of the respiratory failure, the patient died. The responsibility of the splenectomy in this infection with many different organisms and the failure of antibiotics is discussed.