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Biomedical subjects

R M Shore

Publications and source records attributed to R M Shore.

28 records · Page 2Linked to original sources
PubMed1982

Acute renal artery occlusion: the role of collateral circulation.

It is not known if no when the probability of success is sufficient to warrant emergency revascularization of acute renal artery occlusion. This probability depends on the ability of collateral circulation to maintain viability. The role of collateral circulation in maintaining renal viability during six and 48 hours of renal artery occlusion has been studied in mongrel dogs. Collateral circulation is sufficient to maintain renal viability beyond the three hours of warm complete ischemia known to cause infarction. It is not sufficient to prevent progressive loss of renal function. Hypertension frequently results. Emergency revascularization of acute bilateral renal artery occlusion, therefore, is indicated. It is not indicated for unilateral occlusion with adequate contralateral function because of the high probability of resulting hypertension.

Acute Disease↗
PubMed1982

Skeletal demineralization in Turner's syndrome.

The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones of girls who received estrogen replacement therapy were less demineralized than those of the others. The bone mineral deficit became less pronounced with advancing age. It could not be determined if the apparent effect of estrogens was related to age or if the apparent improvement with age was really due to an effect of estrogen treatment. For 8 subjects followed longitudinally there was no significant change in the BMC deficit.

Adolescent↗
PubMed1982

Dual radiopharmaceutical imaging in congenital asplenia syndrome.

Asplenia was suspected in one patient with combined immunodeficiency syndrome and 5 with congenital cardiac anomalies who had Howell-Jolly bodies on peripheral blood smears. 99mTc-sulfur colloid scans were equivocal for absence of the spleen. When they were compared with the 99mTc-PIPIDA hepatobiliary images, a discrepancy in organ morphology between the two scans indicated that the spleen was present, whereas similarity of the two images suggested asplenia. This procedure was useful in establishing asplenia in 4 patients and confirming the presence of a rudimentary or ectopic spleen in 2 others. Unequivocal demonstration of the spleen on the sulfur colloid scans makes the hepatobiliary study unnecessary, while unequivocal demonstration of a normal-appearing liver without splenic activity may warrant a tagged red-cell study for a more complete evaluation.

Erythrocyte Inclusions↗
PubMed1982

Lateral cervical meningocele.

Although lateral meningoceles have been described in the thorax, they have not been previously reported in the neck. We describe an infant who was born with a lateral meningocele in the cervical posterior triangle that was felt clinically to be cystic hygroma. Surgical excision was complicated by a cerebral spinal fluid fistula and subsequent meningitis. Problems that this patient presented and potential complications in management are discussed. Although the clinical manifestations of lateral meningoceles and extradural cysts are quite different, there are many anatomic similarities between these entities and other cervical masses that confuse diagnosis and nosology. Their differential diagnosis is reviewed.

Cervical Vertebrae↗
PubMed1981

Osteopenia in juvenile diabetes.

The bone mineral status of fifty-one children with diabetes mellitus was studied by single photon absorptiometry. The mean bone mineral content was 13% below values predicted by age, sex, height, and weight. Those children whose diabetes was one year or less in duration were as osteopenic as those whose diabetes was of longer duration. The demineralized children received a higher daily insulin dose than others. No association was noted between the degree of skeletal demineralization and sex, statural growth, renal function, and serum calcium and phosphorus. No significant changes in bone mineral content were noted longitudinally.

Child↗
PubMed1981

Adrenal scan in 17-alpha-hydroxylase deficiency: false indication of adrenal adenoma.

A patient who was thought to have testicular feminization syndrome and primary aldosteronism had an adrenal scan that suggested an adrenal adenoma. After later diagnosis of 17-alpha-hydroxylase deficiency, she was treated with glucocorticoids rather than surgery. Her clinical course and a repeat adrenal scan confirmed she did not have a tumor.

Adenoma↗
PubMed1980

Bone mineral status in growth hormone deficiency.

Bone mineral status was monitored by photon absorptiometry in 18 children with growth hormone deficiency. Before exogenous growth hormone therapy, bone mineral content, bone width, and BMC/BW were below predicted values. Delayed maturation, as assessed by skeletal age, accounted for approximately 35% of the deficit for these values. Height velocity doubled during therapy, and BMC, BW, and BMC/BW increased commensurate with height and weight increases so that the relative deficit was unchanged. The pathogenesis of relative osteopenia in growth hormone deficiency was not determined.

Adolescent↗