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Biomedical subjects

R Mahler

Publications and source records attributed to R Mahler.

11 recordsLinked to original sources
PubMed1991

Diabetologists' assessments of their outpatients' emotional state and health beliefs: accuracy and possible sources of bias.

The accuracy of physicians' perceptions of their patients' emotional state and health attitudes was examined in a diabetes outpatient clinic by comparing patients' ratings of anxiety, depression and health locus of control with physicians' ratings. In 234 patients, doctors' and patients' ratings correlated significantly for depression and anxiety. The physicians rated patients with a strong belief in control of health by others as most dependent on doctors. Men but not women with external locus of control were also rated as very dependent on doctors. Anxious or depressed patients were rated by their doctors as less able to cope with diabetes. The results indicate that non-psychiatric physicians are able to assess their patients' emotions and health attitudes with greater accuracy than is usually assumed.

Adaptation, Psychological↗
PubMed1990

Clostridial pleuropulmonary infections: case report and review of the literature.

Clostridia rarely cause pleuropulmonary infections in the absence of trauma. We report a case of intermittent bowel obstruction, clostridial bacteraemia and pneumonia with a fatal outcome. Only 16 cases have previously been reported. Clostridial infection of the lung has many features of an acute pneumonia and is almost always associated with a pleural effusion. Most cases are caused by Clostridium perfringens, though infections with other species have been reported. The prognosis is generally more favourable than in clostridial infection secondary to aspiration pneumonia or complicating empyema.

Aged↗
PubMed1987

Effect of chloroquine on insulin and glucose homoeostasis in normal subjects and patients with non-insulin-dependent diabetes mellitus.

Plasma glucose, insulin, and C peptide concentrations were determined after an oral glucose load in normal subjects and in a group of patients with non-insulin-dependent diabetes mellitus before and during a short course of treatment with chloroquine. In the control group there was a small but significant reduction in fasting blood glucose concentration but overall glucose tolerance and hormone concentrations were unaffected. In contrast, the patients with non-insulin-dependent diabetes mellitus showed a significant improvement in their glucose tolerance, which paralleled the severity of their diabetes. This response seems to reflect decreased degradation of insulin rather than increased pancreatic output. These observations suggest that treatment with chloroquine or suitable analogues may be a new approach to the management of diabetes.

Aged↗
PubMed1986

Pigmentation induced by quinidine therapy.

Abnormalities of pigmentation are a well-known side effect of antimalarial therapy. Quinidine, an antiarrhythmic agent, is structurally related to the common antimalarials but, to our knowledge, has not been associated with pigmentary abnormalities. We report a case of localized blue-gray pigmentation, clinically and histologically identical to antimalarial-induced pigmentation, in a patient receiving quinidine therapy.

Aged↗