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R Marczewski

Publications and source records attributed to R Marczewski.

5 recordsLinked to original sources

[Evaluation of using fibrin tissue adhesive (Beriplast) and preparations of thrombin and adrenalin in injection hemostasis methods for gastric and duodenal ulcer hemorrhage. Randomized, prospective clinical trial].

A prospective randomized trial involving 30 patients was performed to assess whether second-look endoscopy could improve the efficacy of injection therapy for bleeding peptic ulcers. The inclusion criteria were the presence of active arterial bleeding or a non-bleeding visible vessel at emergency endoscopy. All the patients received emergency injection of thrombin with adrenaline solution and were subsequently randomized (15 patients in each group). All the patients receive a second elective endoscopy within the first 24 hours with repeated injection of thrombin-adrenaline solution (Group I) or fibrin sealant-Beriplast-(Group II). A tendency towards better results was noted in the Group II. Recurrent bleeding was observed in 6.6% versus 26.6% patients in Group I. The need for emergency surgery occurred in (6.6% in Group I versus 0 in Group II) and length of hospital stay was (13.2 in Group I versus 7.4 in Group II [p < 0.05]). No mortality was observed in both of the groups. In conclusion, our data suggest the possibility of a small benefit with second-look endoscopy with repeated injection of fibrin sealant.

Adult↗

[Thyroid cancer in material of the II Department of Surgery, Medical University of Gdansk].

The aim of study is an evaluation of the diagnostic methods and results of surgical treatment 202 patients suffered from thyroid cancer. Those patients were operated on in II Department of Surgery Medical University of Gdańsk in the years 1950-1993. There were 146 female and 56 males. Most frequently histological finding was papillar cancer--71 cases, follicular cancer in 57 cases, medullar cancer in 31 cases and anaplastic cancer in 43 cases. FNB diagnosis of the cancer was established 89% of the patients before operation, during operation in 96% cases. In the majority of the patients with papillar cancer total thyroidectomy were carried out but the medullar and anaplastic cancer this treatment was possible only in small numbers of cases. In majority of those patients adjuvant treatment was performed. 128 patients with well-differentiated thyroid cancer was treated 131. Radiotherapy have been applied in all patients with medullar and anaplastic cancer. In cases of well-differentiated thyroid cancer the serum thyroglobulin level was also determined.

Adolescent↗

The role of endoscopic thrombin injections in the treatment of gastroduodenal bleeding.

One hundred and ninety-one patients who had emergency endoscopy performed for acute gastroduodenal haemorrhage and were found to be bleeding actively (N = 141) or to have an ulcer containing a non-bleeding visible vessel (N = 50) were studied. Patients with active bleeding were divided into two groups: group I included 47 patients in whom diagnostic endoscopy was performed and conventional management applied; and group II contained 94 patients in whom, apart from conventional treatment, endoscopic thrombin injections could also be offered. Fifty patients with non-bleeding visible vessels were admitted to a prospective randomised trial and assigned to either endoscopic injections (group A, N = 25), or no primary endoscopic treatment (group B, N = 25). The introduction of the injection therapy in patients who were actively bleeding resulted in a significant reduction of the emergency operation rate (70.2% v. 12.8%; P < 0.001), mortality rate (21.3% v. 8.5%; P < 0.05 and blood transfusion requirements (4,220 +/- 1,840 ml v. 1,980 +/- 980 ml; P < 0.05). Endoscopic thrombin injections of non-bleeding visible vessels reduced the rebleeding rate (40% v. 4%; P < 0.01) and blood transfusions (2,939 +/- 1070 ml v. 1,390 +/- 552 ml; P < 0.05).

Female↗