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Biomedical subjects

R Markello

Publications and source records attributed to R Markello.

14 recordsLinked to original sources
PubMed1975

Cardiovascular effects of oxytocin.

Oxytocin, 5 to 10 units, is frequently given as a bolus injection following term delivery or elective termination of pregnancy. It is not general knowledge that this has any untoward effects. In the present study in young, healthy women undergoing elective termination of pregnancy, mean arterial blood pressure decreased approximately 30% and the total peripheral resistence 50%, 40 seconds after injection. However, heart rate increased 30% and stroke volume 25%, so that the cardiac output was elevated more than 50% above control. Oxytocin given as a dilute solution produced no circulatory change; hence, we suggest that this drug be administered in such fashion rather than by bolus injection.

Abortion, Induced↗
PubMedDate not supplied

Diffusion hyperoxia following preoxygenation.

Several minutes of 100 percent O2 breathing prior to inhalation induction with 79 percent N23 results in consistently higher PaO2 values during the first 10 minutes compared with prior air breathing. The theoretic maximum concentrating action of N2O uptake upon O2 is approximately the same (60 torr) regardless of gas breathed before induction.

Adult↗