Biomedical subjects

R Martín-González

Publications and source records attributed to R Martín-González.

6 recordsLinked to original sources

PubMed1998

[Vertebrobasilar ischemia of thrombotic and embolic origin].

OBJECTIVE: To analyze the mechanisms involved in the appearance of ischemia in vertebro-basilar territory, especially those of embolic or thrombotic characteristics. DEVELOPMENT: The mechanism of vertebro-basilar ischemia had not been adequately studied until a few years ago. This had led to the belief that most were due to a haemodynamic mechanism. However, in recent years studies of large numbers of patients, in whom cardiological and neurovascular evaluation had been systematically carried out, has shown that this is not so. In general, the commonest mechanism is embolism, both of arterial and of cardiac origin. Local thrombosis and a haemodynamic mechanism are less common. The arterial lesions most often associated with intra-arterial embolism have their origins in the intracranial segment of the vertebral artery. The most frequent sites of blockage by emboli are the distal segments of the basilar artery, the superior cerebellar artery, the posterior cerebral artery and the intracranial region of the vertebral artery-posteriorinferior cerebellar artery. CONCLUSIONS: The mechanism of vertebro-basilar ischemia is not homogeneous and can not be taken for granted in any patient in particular. For this reason it is necessary to carry out a full clinical study of patients with these symptoms, similar to that done for patients with carotid ischemia. This permits not only individualized, correct treatment of each patient but also a more complete knowledge of the mechanisms of ischemia in this territory.

Arterial Occlusive Diseases↗

PubMed1997

[Neurology in Internet].

OBJECTIVE: The quantity and complexity of the information to be found on the Internet makes anyone who has dared to navigate on the Net feel perplexed. To access the Net without a predetermined route to follow may prove to be a waste of time and very exasperating, as a tremendous amount of completely irrelevant information is discovered. The objective of this article is to give the reader of the REVISTA DE NEUROLOGIA an informative guide to help find useful information on the Net, and a classified list of potentially useful Internet addresses. DEVELOPMENT: We have analyzed the concept of 'search tool', and the types and characteristics of these. Specific search tools (both English and Spanish) which are currently available, are considered. We have searched the Net using various tool (Yahoo, Lycos, Altavista, Trobador and Olé) to find relevant information for the terms 'neurosciences' and 'neurology', and to verify the relevant interest of the sites on the Net thus encountered. CONCLUSIONS: We present the URL of 50 search tools and the 244 sites on the Net related to Neurology and the Neurosciences, classified according to the entity or group to which they correspond, and their ambit (Latin American/Spanish vs others). A short list of those which may be of most interest is also included.

Computer Communication Networks↗

PubMed1997

[Quality and life style as risk factors in acute cerebrovascular disease].

INTRODUCTION: In some series of patients with acute cerebral vascular disease (CVD) it has been seen that, prior to the episode of CVD, the patients already had a poorer quality of life than other people of their age. The object of this study is to evaluate their previous life style and quality of life as risk factors (RF) in acute CVD. MATERIAL AND METHODS: A case-control study was done of a total of 151 patients admitted to two hospitals with acute CVD and 151 persons, who were not hospitalized and acted as the control group, paired (one to one) for age, sex and hospital. In both groups data were collected regarding basic general health, previous quality of life (Nottingham Health Profile-NHP-, life style and self-perception of social support. The relative risks were estimated by calculating the odds ratios and conditional logistic regression. RESULTS: Regular moderate physical exercise acts as a protective factor with an OR of 0.32 (IC 95%: 0.14-0.76). Consumption of tobacco and alcohol increased the risk of CVD but did not reach statistical significance. No relationship was found between perceived social support and risk of CVD. Physical mobility, evaluated using the NHP showed a statistically significant negative association with acute CVD (OR: 0.32; IC 95%: 0.14-0.71). CONCLUSIONS: Our results seem to suggest that the previous overall quality of life cannot be considered a RF in acute CVD, except for physical mobility as evaluated on the NHP. Reduction of this constitutes a RF and moderate physical exercise behaves as a protective factor.

Acute Disease↗

PubMed1997

[Stressful life events as risk factors in acute cerebrovascular disease].

INTRODUCTION: The influence of psychosocial stress on the origin of acute cerebral vascular disease (CVD) has received very little attention. The objective of this paper is to evaluate the role of psychosocial stress due to events occurring in daily life as a risk factor (RF) in acute CVD. MATERIAL AND METHODS: A case-control study was done of a total of 151 patients who were admitted to two hospitals with acute CVD and 151 persons, who where not hospitalized and acted as the control group, paired (one to one) for age, sex and hospital. In both groups data were collected regarding basic general health, consumption of tobacco and alcohol and stressful incidents (SI) in their lives during the previous two years. The stress derived from SI was measured on the 'Inventory of SI and Recent Experiences' of Holmes and Rahe. The frequency of serious SI was also considered. The relative risks were estimated by the odds ratio calculations. RESULTS: A positive association was found for the RF defined in relation to acute CVD. We did not find any relationship between psychosocial stress derived from SI and risk of acute CVD (either when considering scores on the Holmes and Rahe Inventory or evaluation of serious SI). CONCLUSIONS: Psychosocial stress from SI does not seem to represent a RF in acute CVD.

Acute Disease↗

PubMedDate not supplied

[Life events, quality of life and social support prior to acute cerebral vascular disease, as predictive factors of the quality of life and functional state following stroke].

INTRODUCTION: The repercussion of stroke on quality of life has been evaluated but not the possible relation between the quality of life before and months after an acute stroke. OBJECTIVE: To study the possible relation between quality of life, social support, stressful life events prior to the stroke and quality of life, social support and functional state months after. PATIENTS AND METHODS: A prospective study was made of 34 patients (71.7 +/- 8 years; 19 (56%) men; 15 (44%) women with stroke, by means of two evaluations: personal interview within the first 36 hours (quality of life--Nothingham health profile (NHP)-, perception of social support and stressful life events--Holmes and Rake inventory-) and an interview over the phone 16.5 +/- 5.3 months after the stroke (NHP, perception of social support and functional state--Rankin scale-). RESULTS: Following the stroke there was deterioration in perception of social support (19.8 +/- 3 vs 12.5 +/- 8; p = 0.000) and in the degree of social isolation of the NHP (9.4 +/- 20 vs 21.1 +/- 30; p = 0.03). The only relation found was between the following variables: pain at the first evaluation and pain (r = 0.45; p = 0.007) at the second evaluation; mobility at the first evaluation and emotional state (r = 0.39; p = 0.029) and social support (r = 0.37; p = 0.027) at the second evaluation; sleepiness at the first evaluation and energy (r = 0.55; p = 0.0006), pain (r = 0.39; p = 0.022), emotional state (r = 0.35; p = 0.038), mobility (r = 0.34, p = 0.048) and sleepiness (r = 0.51; p = 0.001) at the second evaluation. CONCLUSION: Our results indicate that there is little relationship between the previous state and that following stroke, and that the deterioration in perception of support and social isolation is due to the stroke itself.

Affect↗

PubMedDate not supplied

[Hyperuricemia as a risk factor for cerebrovascular accident: a case-control study].

INTRODUCTION: Although several collateral studies have been made of the relationship between hyperuricemia and cerebral vascular accidents (CVA), no definite conclusion has been reached. OBJECTIVE: To analyze the possible relationship between hyperuricemia and CVA. PATIENTS AND METHODS: We studied the cases and controls paired for age, sex and hospital. They included patients with CVA (125) and controls (250 ophthalmological patients). Both groups contained 50.4% men and 49.6% women with an average age of 70 +/- 11 years. Data regarding vascular risk factors, a known personal history of hyperuricemia were recorded and serum uric acid levels determined in both groups. The relative risks were calculated using the Odds Ratio (OR) with a confidence interval of 95% (CI 95) and a conditional logistic regression study made. RESULTS: A statistically significant relationship was found between CVA and: arterial hypertension (OR: 6.32; CI 95: 3.43, 11.65); smoking (OR: 3.79; CI 95: 1.36, 10.58); alcoholism (OR: 2.54; CI 95: 1.11, 5.41); ischemic cardiopathy (OR: 2.37; CI 95: 1.2, 4.70) and previous CVA (OR: 5.93; CI 95: 3.17, 11.09). No relation was found with: a history of hyperuricemia (OR: 1.53; CI 95: 0.63, 3.73), serum uric acid levels (OR: 0.86, CI 95: 0.36, 2.00 when the uricemia was between 5 and 5.99 mg/dl and OR: 0.46, CI 95: 0.21, 1.02, when the uricemia was over 6 mg/dl). CONCLUSION: Our results suggest that hyperuricemia is not an independent risk factor for CVA.

Adult↗