[Inappropriate antidiuretic hormone secretion syndrome associated with the use of selective serotonin reuptake inhibitors].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to R Mateos Campos.
Explore the source record for details and available documents.
OBJECTIVES: To quantify the consumption of tuberculosis medication prescribed through the National Health Service in Spain during 1996. To calculate the prevalence of tuberculosis from this consumption. To analyse possible inequalities between autonomous communities. To analyse the cost of these drugs. DESIGN: A crossover, retrospective and observational study. SETTING: Primary care. MEASUREMENTS AND RESULTS: 5533233 DDDs were taken in 1996. 2215890 of these DDDs belonged to the rifinah association (rifampicin + isoniazid), followed by the active principle rifampicin with 973510 DDDs. Amikacin at 8,078 DDDs represented the lowest dose. DID (dose per inhabitant per day) in Spain was 0.37. Dosage was greater in Galicia (0.66) and Ceuta (0.52). The Canaries (0.19) and Balearics (0.27) were below the national average. Use was 40.05% for rifinah, followed by 17.59% for rifampicin. The least common active principles were amikacin (0.14%) and streptomycin (0.74%). The number of cases of tubercular disease in Spain calculated was 11,211; its prevalence was 27.7 cases per 100,000 inhabitants. Total medication cost was 863275147 pesetas (0.1% of total pharmaceutical expenditure). The attributable cost was rifinah, 40.26%, the rifater association, 21.68%, and rifampicin, 18.34%. CONCLUSIONS: The most often prescribed drug is the rifampicin + ilsoniazid association. Use varies between autonomous communities. We think that the prevalence calculated is high for a developed country.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
OBJECTIVE: To assess the level of initial non-compliance with treatment. DESIGN: An observational study with interviews of patients, which compared prescriptions filled at the Siruela Health Centre (Badajoz) with those dispensed at the town's only pharmacy. SETTING: Primary Care; rural ambit. RESULTS: 8,100 prescriptions were filled for an attending population of 3,100 people. 218 (2.7%) were not collected at the pharmacy. Non-compliance was considerably greater among active workers (4%) than pensioners (2%) (Z = 5.3; p < 0.001). Non-compliance was also greater when prescriptions were written by locums at weekends or on bank holidays (8.6%) than when they were written by the normal doctor (2.2%) (Z = 9.8, p < 0.001). 50.9% of prescriptions not collected were for pensioners on Social Security and 49.1% for the active population. Causes of non-compliance indicated by the patients were: medicine had little effect (33%), high price (28.4%) and not financed by the National Health System (26.6%). 32.6% of the cases of non-compliance were followed up; 64.8% of them returned to the consultation. CONCLUSIONS: Better information to patients on their pathologies and treatments would avoid many cases of non-compliance.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Information on pharmaceutical assistance in health care can be obtained from different sources: pharmacies, medical records, market studies, and family interviews. These allow to evaluate whether the consumed drugs were prescribed or directly purchased, if they are stored at home, and the relation between these facts and the familial characteristics. In the present study we have carried out a comparative analysis of data related to the use of drugs in the Salamanca Province depending of their source: the doctors or the families themselves. We distributed by post a questionnaire to the primary care physicians. We also interviewed a representative sample of the families of the Salamanca Province. We found that those drugs most commonly prescribed by doctors were also the most commonly reported as used by the families: drugs for cardiovascular disease, anti-inflammatory-antirheumatic drugs, and analgesics.
Health authorities need to have knowledge of the use of health services in order to be able to adopt suitable measures that will ensure a more rational use of pharmaceutical products. The information relative to drug consumption and expenditures can be obtained from different sources. In the present study a survey was carried out by interviewing Salamanca families in order to discover their degree of drug consumption and the expenses incurred therein. The drugs consumed by most families were analgesics-antiinflammatory agents and cardiovascular agents. Most families were found to spend less than 1000 pesetas per month. The expenses incurred were seen to depend on the family characteristics: age, educational status and income.
Explore the source record for details and available documents.