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Biomedical subjects

R Matz

Publications and source records attributed to R Matz.

At least 73 records · Page 4Linked to original sources

Post-hypoxic leukoencephalopathy with late recovery.

A man developed severe spastic quadriplegia following a mixed drug overdose-induced coma. Diagnostic studies were consistent with hypoxic leukoencephalopathy. The patient made a dramatic functional recovery 3 1/2 months after admission, with Computed tomography scan and EEG findings returning to normal. The time course of recovery suggests that remyelination may have taken place. This case illustrates the importance of early and continued vigorous rehabilitation therapy for patients in whom late recovery from critical illness is possible.

Adult

Hyperosmolar coma.

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Diabetic Coma

Lactic acidosis.

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Acidosis

High elevations of creatine phosphokinase in hypothyroidism. An isoenzyme analysis.

In hypothyroidism, slight elevations of serum creatine phosphokinase (CPK) levels are common. In contrast, we describe six hypothyroid patients with extreme elevations (17- to 160-fold) of CPK levels. Enzyme analysis showed only MM isoenzyme in four cases and MM plus trace MB isoenzyme in two patients. Hypothyroidism should, therefore, be considered when elevated CPK levels, even extreme, are found. Isoenzyme analysis in such a case will show primarily an MM pattern, although trace MB fraction can also be seen. This isoenzyme pattern suggests that the sources of the CPK elevations is skeletal muscle.

Adult

Reorganization of ambulatory health care in an urban municipal hospital. Primary care and its impact on hospitalization.

Ambulatory care services have been reorganized in a New York City hospital. A newly developed Neighborhood Family Care Center (NFCC) replaced the outpatient clinics. The NFCC and both inpatient and emergency services are totally integrated so as to overcome many of the deficiencies that previously existed in ambulatory care, such as inferior quality of care, minimal academic involvement, fragmentation of services, overspecialization, and unresponsiveness to patients' needs. A review of all patients admitted to the Adult Medical Service has shown a statistically significant decrease in admission rates for diabetic coma-acidosis, severe hypertension, congestive heart failure, cerebrovascular accidents, and severe asthma during the 18 months following the reorganization of ambulatory care. Analysis of cost effectiveness of these changes on the utilization of hospital beds indicates the potential for reduced expenditures of limited health care dollars.

Ambulatory Care