One hundred fifty human cadaver kidneys have been preserved by a combination of topical hypothermia and pulsatile perfusion with cryoprecipitated plasma in our laboratory. Post-transplant acute renal failure was reduced from 58 to 21 per cent in those kidneys protected with furosemide and methylprednisolone.

Acute Kidney Injury↗

PubMed1975

Prolongation of allografts in animals with a new agent: tilorone.

Tilorone, a synthetic amino-alkoxyflorenone, has been demonstrated to prolong allografts in rats and dogs. Tilorone, in combination with low dose non-specific immunosuppression, appears to have an additive effect. Tilorone's mechanism of action is unclear at this time but may involve a combination of specific T lymphocyte depletion and interferon induction.

Animals↗

PubMed1973

The importance of donor protection by furosemide and steroids in cadaveric kidney preservation.

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Cadaver↗

PubMed1971

Successful preservation and simultaneous transplantation of human cadaver kidneys.

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Cadaver↗

PubMed1971

Grenz ray treatment of basal cell carcinoma.

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Adult↗

PubMed1968

Megacholedochus. A condition arising from long-standing biliary tract obstruction in the patient with cholecystectomy.

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Aged↗

PubMedDate not supplied

Resolution of acute renal failure in toxoplasmic encephalitis despite continuance of sulfadiazine.

A patient with AIDS and toxoplasmic encephalitis treated with pyrimethamine and sulfadiazine became hypovolemic and developed acute renal failure. Diagnostic sulfadiazine crystals were abundant in the urine, and ultrasound examination demonstrated sludge and stones, presumably due to sulfadiazine. Renal failure resolved rapidly with hydration and administration of alkali, despite continued administration of sulfadiazine. The relatively old literature concerning crystalluria and renal failure due to sulfonamides is reviewed briefly, since complications due to use of poorly soluble sulfonamides probably will become more widespread as toxoplasmic encephalitis becomes more prevalent.

Acquired Immunodeficiency Syndrome↗