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Biomedical subjects

R Merchant

Publications and source records attributed to R Merchant.

5 recordsLinked to original sources
PubMed1990

Correlation between integrated evoked EMG and respiratory function following atracurium administration in unanaesthetized humans.

In six healthy volunteers, integrated evoked electromyography (IEEMG) measured in response to ulnar nerve stimulation was correlated with respiratory function-tidal volume (VT), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), maximum negative inspiratory pressure (NIP), hand grip (HG) and head-lift during steady-state infusion of subparalytic doses of atracurium. Studies were carried out at train-of-four T4/T1 = 0.2 and T4/T1 = 0.6. When T4/T1 = 0.2, all subjects had difficulty with swallowing and phonation, none could sustain any head-lift and HG was 26 per cent of control. However, VT was normal, FVC was 80 per cent, FEV1 was 82 per cent, and NIP was 50 per cent of control. AT T4/T1 = 0.6, all assessments of peripheral strength were normal, and all respiratory measurements were not significantly different from control, except for NIP which was 73 per cent of control (P less than 0.05). We conclude that an IEEMG of 0.6, recorded from the hypothenar muscles, in unanaesthetized subjects is consistent with near normal respiratory function.

Adult↗
PubMed1989

Endoscopy in the diagnosis of genital tuberculosis.

From 1977 to 1986, endoscopy (laparoscopy, cystoscopy and hysteroscopy) was used in the evaluation of women for pelvic tuberculosis. Among 687 cases of diagnostic laparoscopy, pelvic tuberculosis was suspected in 101 (14.7%) from the appearance alone. The appearance was correlated with other criteria for the diagnosis. Definitive evidence was found in 70 cases. All 101 patients were placed on an antibiotic. Seventy-three patients reported for follow-up for more than two years. Of them, six (8.2%) were judged to be cured. Thirty-eight (52.05%) improved as determined by second-look laparoscopy and/or negative histopathology or hysterosalpingographic evidence. Eleven women (15.06%) had an intrauterine pregnancy; nine delivered normally, and two underwent termination of pregnancy for medical reasons. There were three tubal pregnancies (4.1%). In 15 cases (20.5%) the disease remained stationary.

Cystoscopy↗