Biomedical subjects

R Meuser

Publications and source records attributed to R Meuser.

4 recordsLinked to original sources

PubMed1995

Chlamydia trachomatis RNA polymerase alpha subunit: sequence and structural analysis.

We describe the cloning and sequence analysis of the region surrounding the gene for the alpha subunit of RNA polymerase from Chlamydia trachomatis. This region contains genes for proteins in the order SecY, S13, S11, alpha, and L17, which are equivalent to Escherichia coli and Bacillus subtilis r proteins. The incorporation of chlamydial alpha subunit protein into the E. coli RNA polymerase holoenzyme rather than its truncated variant lacking the amino terminus suggests the existence of structural conservation among alpha subunits from distantly related genera.

Amino Acid Sequence↗

PubMed1970

Multivalent regulation of glutamic dehydrogenases from fungi. Effects of adenylates, guanylates, and acyl coenzyme A derivatives.

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Adenine Nucleotides↗

PubMed1969

Kinetic analyses of the regulation of glycogen synthetase activity in zoospores and growing cells of the water mold, Blastocladiella emersonii.

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Adenosine Triphosphate↗

PubMedDate not supplied

56K fibroblast protein not specific for Duchenne muscular dystrophy but for skin biopsy site.

Recently, we reported the detection by two-dimensional gel electrophoresis of a 56,000 (56K)-molecular weight polypeptide that was present in cultured skin fibroblasts from normal males but was not detectable in fibroblasts from Duchenne muscular dystrophy (DMD) patients. Since then we have established that the 56K polypeptide is not present in skin fibroblasts from normal females, DMD carrier females, or in normal male fibroblasts obtained from sources other than the Repository for Mutant Human Cell Strains, Montreal. Further inquiry has led to the discovery that all the normal male fibroblast cultures obtained from the Montreal repository had been established from preputial skin. Fibroblast cultures from DMD patients, DMD carriers, as well as other normal individuals, had been derived from non-genital skin biopsies. Thus, the absence of the 56K polypeptide is not specific for DMD, but rather is related to the site of skin biopsy.

Biopsy↗