Alopecia areata totalis/universalis and systemic corticosteroids.
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Biomedical subjects
Publications and source records attributed to R Michalowski.
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Sections from the wheals of recent onset 24 hours old or less taken from 11 patients with urticaria were examined by electron microscopy. The results have demonstrated that some langerhans cells display cell structure damage, namely: vacuolation of cytoplasm, damage to some mitochondria, prominent golgi complex and rough endoplasmic reticulum. The Birbeck granules have shown various forms. These findings suggest that in urticaria, the langerhans cells take part in the allergic reactions.
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The unique case of a self-inflicted cheilorrhagia with clinical features of Munchausen syndrome and cheilitis glandularis is described. Attention is directed to the association of cheilitis glandularis and factitious bleeding. This constitutes a new variety of bleeding type Munchausen's syndrome.
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The unique case of a 33-year-old man with a silica granuloma at the site of circumcision, performed 15 years previously for acquired phimosis, is reported. The lesion was probably produced by the deposit of talc in the surgical wound.
A case of acquired atypical erythrokeratoderma in a 16-year-old boy is reported. Most of the lesions were localized at the periorificial areas of the body, mainly at the angles of the mouth, the lower lip, as well as in perinasal, genital, and perianal regions. They were associated with acral involvement and pachyonychia. There were no similar skin lesions in the patient's family. The author regards the present case as an erythrokeratoderma periorificialis on the basis of an own observation and the data from the literature.
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Glans penis and foreskin lesions occurred in sixteen patients (+/- 34 p. 100) in a group of 46 males with trichomoniasis and were predominantly of the erosive type. Trichomonal balano-posthitis has been associated with trichomonal uretritis in 7 patients, with syphilis in 4 patients and with genital warts in 4. The dominant complication was phimosis. Long foreskin should be considered a favorable condition in infection of glans penis and foreskin due to T. vaginalis. The dense predominantly lymphocytic infiltration in the upper dermis characterized the histology of the lesions. An inguinal lymph node biopsy specimen demonstrated the features of reactive hyperplasia, a cause of inguinal lymphadenopathy. The condition responded well to treatment with metronidazol during 9-10 days.
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