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R Minck

Publications and source records attributed to R Minck.

35 records · Page 2Linked to original sources

[Group B streptococci: serotyping data and susceptibility to antibiotics (author's transl)].

A study of the prevalence of group B streptococci in women (covering 6,000 samples) shows the vaginal presence to be comprised between 6.34 and 16.8%. The highest rate is found in a Centre for venereal diseases. The use of selective media results in a 50 to 75% increase in the number of germ-carries. The distribution found after serotyping of 1,469 strains has been studied. Over half of the strains isolated from the vagina and from infants belong to serotype II and III, one third of the strains causing serious infections are of type III; however, there is a wide dispersion of the serotypes found in neonatal infections. The test for pigmentation on Columbia medium offers an excellent approach for the diagnosis of group B streptococci. MIC testing of 7 antibiotics for 782 strains of various serotypes demonstrates high susceptibility to the beta-lactam antibiotics and makes it possible to detect rare strains with features of polyresistance to chloramphenicol and some macrolide antibiotics.

Adult↗

Corynebacterium group D2 ("Corynebacterium urealyticum") constitutes a new genomic species.

Twenty-one Corynebacterium group D2 ("C. urealyticum") strains were found to constitute a tight DNA hybridization group distinct from named Corynebacterium species. The strains of Corynebacterium group D2 had cell wall component type IV, short chain mycolic acids and G+C content of DNA of 65-66 mol %. Corynebacterium group D2 constitutes a genomic species which can be identified by phenotypic tests.

Base Composition↗

[The importance of Lancefield Group B streptococci (S. agalactiae) in gynaecology and obstetrics (author's transl)].

A bacteriological study of 10,962 vaginal swabs has made it possible to work out the percentage of women who are carriers of Group B streptococci in their vaginas. The count varies between 9.43 and 17.25 per cent according to the different populations that were studied. Serotyping of the strains of 1,030 vaginal specimens was carried out and it was found that serotypes II and III predominated. We have been able to study 27 strains responsible for infection in the early neonatal period such as septicaemia or meningitis at the same time as we were studying the vaginal flora. The distribution of the serotypes illustrates a predominance of types 1c and III in 70 per cent of cases. Contamination between the mother and the child is obvious but in 95 per cent of cases the strain isolated in the infected child was of the same serotype as that which was isolated in the mother. Group B streptococci are still very sensitive to antibiotics and particularly to the penicillins. It does seem to us to be unrealistic to treat with antibiotics prophylactically in pregnancy. On the other hand careful attention to the newborn and careful bacteriological study of multiple specimens taken from the skin and the orifices gives easy screening for the germ and the possibility of treating infants that are grossly contaminated.

Carrier State↗

[Usefulness of micro-organism counts in positive haemocultures (author's transl)].

In patients with positive haemoculture counting the number of micro-organisms per ml of blood can be of interest for both diagnosis and prognosis. Contamination is practically excluded when values exceed 20 organisms/ml, and bacteraemia when they exceed 500 organisms/ml. Generally, the higher the count the greater the likelihood of septicaemia. Values lower than 2 organisms/ml correspond in most cases to Gram-negative infections. Excluding the latter, which carry a high lethal risk, the mortality rate in septicaemia increases with the number of micro-organisms in the blood.

Bacteriological Techniques↗