Several indices of coagulation and fibrinolysis were studied in 54 patients suffering from Schönlein-Henoch disease. A significant prolongation of platelet aggregation was found in parallel with a decrease of AT III and plasminogen and an increase of the fibrin monomer complexes. Consequent to heparin treatment controlled by measurements of residual thrombin activity, the indices showed a trend towards normalization. The dynamic monitoring of the above indices can be used for an overall assessment of the heparin treatment.

Adult↗

PubMed1988

[Histamine content and function of the mastocytes of the skin in patients with Schoenlein-Henoch disease].

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Adolescent↗

PubMed1987

[Immunological control of heparin treatment of patients with Schoenlein-Henoch disease].

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Adult↗

PubMed1986

[Pathogenetic aspects of Schönlein-Henoch disease].

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Antigen-Antibody Complex↗

PubMed1984

[Immunological changes in Schönlein-Henoch patients].

The level of serum IgI, A, M, complement titre and circulation immune complexes were studied under clinical conditions of 17 patients with Schönlein-Henoch, active phase. The following changes were established as compared with the control, healthy subjects: four-times increased values of the circulating immune complexes, elevated IgA serum level, and IgG--to a lesser degree and reduced titre of the complement. Prognosis is more unfavourable in patients with extremely high values of the circulating immune complexes and complement consumption.

Adult↗

PubMed1974

[Hematologic and enzymatic tests in agricultural workers with acute intrathion poisoning].

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Acute Disease↗