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Biomedical subjects

R Monno

Publications and source records attributed to R Monno.

69 records · Page 4Linked to original sources

[Effects of anesthesia and surgical trauma on the immune response of pediatric patients].

The AA. have evaluated the effects of anaesthesia and surgical trauma on the ability of lymphocytes from 10 patients to release Leukocyte Inhibiting Factor (LIF) after stimulation with phytohaemoagglutinin (PHA). In addition, they have studied the electrophoretic mobility of Polymorphonuclear-cells (PMN) and lymphocytes of 8 patients after incubation in autologus plasma. The experimental results show decrease of LIF production after operation in 6 individuals and reduction of eletrophoretic mobility of PMN and lymphocytes. The last finding is not significant on statistical point of view.

Adolescent↗

[Recent data about microorganisms of the genus Serratia (author's transl].

The Authors on the basis of most recent references, expose the epidemiological, cultural, biochemical and taxonomical characteristics of microorganisms of the genus Serratia. In addition the most recent data regarding the typing and the sensitivity to antibacterial agents are discussed.

Anti-Bacterial Agents↗

[Toxic activity of Legionella pneumophila: current findings and prospects].

The AA. report the personal contributions and the recent findings of other investigators dealing with the toxic activities of Legionella pneumophila, the causative agent of Legionnaires' Disease. From the results of some tests (particularly Limulus endotoxin assay, pyrogenic reaction, skin Shwartzman reaction) there is an increasing evidence that Legionella pneumophila possesses some of the in vitro and in vivo biological properties associated with endotoxins of Gram negative bacteria, even if to a different of potency in different strains. However, the exact roles of an endotoxin and other bacterial products (e.g. haemolysins) as a pathogenetic mediators of the pathophysiological events of the disease remain to be determined.

Animals↗

[Endotoxemia and phagocytic function in premature infants. II. Role of the blood platelets].

The AA. have studied the relationship between endotoxaemia, detected in premature children and platelets function, according to the most recent finding, supporting the presence of specific receptors for endotoxin at the surface of thrombocytes. The finding of 6 positive Limulus test on platelets over 7 cases support the ability of clearance from platelets towards endotoxin. Furthermore, the AA. suggest that the presence of endotoxaemia in the plasma is due to an impairment of more complex mechanism, as liver's detoxification, which seems the most important.

Blood Platelets↗

[Endotoxin content of samples of pasteurized milk: preliminary findings].

By Limulus lysate assay, endotoxin was found in pasteurized milk samples from commercial source. The range was 32 to 128 microgram per ml, without any change when the samples were refrigerated. By contrast, the endotoxin content rose 512 to 2048 microgram per ml when milk was maintained at room temperature for 24 hours and 1024 to 6400 microgram per ml when samples were examined after 72 hours. These findings suggest a possible clinical implication, and support the concept that Limulus assay appears to be a rapid, reliable, and sensitive test for a quality control in commercial milk samples.

Animals↗

Endotoxemia detected by Limulus assay in severe malnourished children. Plasma effects on leucocyte migration: preliminary investigations.

The Authors have examined 10 cases of severe malnourished children (7 cases of kwashiorkor, 2 cases of marasmus, 1 case of marasmic kwashiorkor). Experiments were carried in order to detect endotoxemia by means of Limulus test, bacteremia with blood cultures and possible effects of plasma on leucocyte migration by Leucocytes Migration Agarose Test (LMAT). The relationship between severe malnutrition, endotoxemia and leucocytes migration has been discussed.

Arthropods↗