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Biomedical subjects

R Mooney

Publications and source records attributed to R Mooney.

44 records · Page 3Linked to original sources

Fetal activity in 100 normal third trimester pregnancies.

The incidence of fetal breathing movements (FBM), fetal trunk movements (FTM), and total fetal activity (TFA) was assessed in 100 normal pregnancies between 28 weeks and term. One 30-minute recording was made from each patient between 0900 and 1700 hours. The mean incidences of FBM, FTM and TFA were respectively 37 +/- 26 (SD) per cent, 18 +/- 10 per cent, and 53 +/- 24 per cent. The mean breathing rate was 48 +/- 12 per minute, and the mean nunber of movements per 30-minute study period was 29 +/- 15. There was a slightly higher incidence of FBM postprandially, but this failed to reach statistical significance. The mean incidence of FBM was lower before 31 weeks and after 40 weeks, compared to that between 31 and 40 weeks, when the values of FBM and FTM were constant. The breathing rate was directly related to gestational age. The mean number of movements per 30-minute study period was inversely related to gestational age, but the duration of movements increased progressively towards term, so that the incidence of FTM was constant throughout the third trimester. There was only one recording of TFA below 10 per cent.

Adolescent↗

A long term clinical study evaluating the effect of two dentifrices on oral tissues.

1. A long term (54 months) supervised, double-blind human clinical study has been conducted to ascertain whether the routine use of a commercially available cosmetic dentifrice, with purported stain removal and flavor impact characteristics, would cause adverse manifestations in the oral tissues, as compared to the similar use of a more conventional type of commercially available dentifrice. 2. One hundred and twenty male and female subjects (aged 12 to 70) were randomly assigned to the use of one of the two dentifrices under investigation, after which they used the assigned dentifrices twice daily (1 min each brushing) under supervised conditions for a period of 54 months. 3. Clinical examinations were conducted on all subjects initially (base line), and at 3-month intervals throughout the 54-month course of the study. This examination included a complete and thorough inspection of the oral soft and hard tissues. 4. The results after 54 months of continuous use of the dentifrices (representing a total dentifrice/oral tissues exposure time of approximately 45 hours per subject) indicated that neither of the two dentifrices caused any adverse reactions of the oral soft tissues and that both dentifrice groups had similar patterns and levels of cervical abrasion and/or erosion. 5. The results also indicate a lack of direct correlation between laboratory abrasivity values (as determined by a radioactive dentin abrasion procedure) and the clinical situation, thus suggesting that factors other than dentifrice abrasivity may play an important role with regard to tooth wear.

Adolescent↗

Effects of age, parity, and adherence on pelvic muscle response to exercise.

OBJECTIVE: To examine factors that affect pelvic muscle response to 12 weeks of pelvic muscle exercise. DESIGN: Repeated measures design in which intravaginal pressures during pelvic muscle contractions were recorded at baseline and after four exercise levels. SETTING: College of Nursing research site in Gainesville, Florida. PARTICIPANTS: Eighty-five parous, community-dwelling women, aged 35-78 years and without incontinence as a primary concern. INTERVENTIONS: A 12-week graded program of regular (three times per week, every other day) pelvic muscle exercise at home. MAIN OUTCOME MEASURES: The hypotheses were that younger age, lower parity, higher baseline intravaginal pressures, and adherence to the pelvic muscle exercise program each would result in significant improvement in maximum intravaginal pressures. RESULTS: The only factor showing significance in predicting a successful outcome was age (t = -2.29, df = 41, one-tail probability = .0136). CONCLUSIONS: Regular, graded exercise over several weeks is needed to build pelvic muscles, and some women who exercise do not improve. Although the reasons for not improving are unclear, age is a significant factor.

Adult↗

The effect of circumvaginal muscle (CVM) exercise.

Circumvaginal muscle (CVM) home training based on principles of exercise physiology were tested on 48 healthy reproductive-age women. The effect of CVM exercise with a resistance device in place, CVM exercise without a device, and no exercise with device in place was studied. After random assignment to home training, CVM assessment was carried out prior to and after 6 weeks of CVM training at home. Each subject served as her own control and change scores of the three groups, on CVM variables were subjected to analysis of variance. Peak maximum pressure (PMP) was significantly different for the three groups. F = 4.56, df = 2.45, p = .016. PMP of exercise without a device was significantly different from the no exercise group (Dunett's test). Analysis of measurement error between- and within-subjects showed that the inherent variability between women was approximately four times larger than the measurement error. The results support the prescription of CVM exercise to hypertrophy the CVM, and indicate that further investigation of the large variance found in the pressure data is needed.

Adult↗