[Value of the determination of a monoclonal CEA (CEA MARIA) in the diagnosis of neoplastic serositis].
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Biomedical subjects
Publications and source records attributed to R Muñiz.
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We present a 59 year old patient diagnosed of right superior lobe pulmonary carcinoma by CT scan. A ventilation/perfusion pulmonary scintigraphy quantified for study of pulmonary function after surgery was performed. The images show an abnormal pattern of the distribution of macroaggregate albumin (MAA) and extrapulmonary presence of tracer (right/left shunt). A first step dynamic study showed the existence of superior cava stenosis and passage of the tracer from the vena cava to the left pulmonary artery by collateral circulation (innominate vein) that not only explained the existence of the abnormal pattern of the MAA distribution but also what the cause of the right/left shunt was. After the resolution of the stenosis, the distribution pattern became normal and the extrapulmonary presence of MAA disappeared.
A group of medical students were interviewed using the 'Alcoi 1992' questionnaire based on the diagnostic criteria of the International Headache Society (IHS) in order to assess the prevalence and various characteristics of migraine. This questionnaire for headache diagnosis was approved in 1993, showing both high sensitivity and exactness in diagnosing migraine. Sensitivity, exactness, predictive value and agreement index of the questionnaire in migraine diagnosis were 100%, 94%, 90% (positive) or 100% (negative) and 0.71% respectively. The group was made up of 96 students of both sexes, with an average age of 23.3 years (standard deviation 1.87). A total of 92 students, 35 male and 57 female, reported headaches. The total prevalence rate for headache was 95.8%, the reliability interval (RI) being 76.7-114.9. In the case of female students, the prevalence rate for headache was 96.6% (RI 71.7-121.5) and in the case of male students it was 94.6% (RI 63-125.7). A total of 20 students, six male and 14 female, fulfilled the criteria for migraine. The overall prevalence rate for migraine was 20.8% (RI 11.9-29.7), the prevalence for females being 23.7% (RI 11.6-35.8) and that for males 16.2% (RI 3.7-28.7). The questionnaire would appear to be a useful, rapid and simple method in the assessment of migraine diagnostic.