Biomedical subjects

R N Bartelt

Publications and source records attributed to R N Bartelt.

5 recordsLinked to original sources

PubMed1986

[Endocrinologic reactions following exposure to fluorescent lamps].

Some reports on an increase of malignant skin tumors following fluorescent lighting made us investigate the systemic effects after exposure to fluorescent rays. Fluorescent rays induce small wavy fluctuations of the plasma concentration of alpha-MSH within normal ranges. Some test persons revealed a steep increase of cortisol values shortly after beginning of fluorescent lighting, indicating that fluorescent rays may induce endocrinological reactions. The significance of these findings with regard to the development of diseases, however, cannot be assessed by now.

Adrenocorticotropic Hormone↗

PubMed1985

[Endocrinological reactions following UV A whole body irradiation].

The basal secretion of proteo-hormones alpha-MSH and ACTH in plasma as well as the changes of the plasma concentrations following UV A-whole-body irradiation were investigated on 40 young male volunteers with different pigmentation levels (Caucasians: skin types I, II, III. Blacks: skin type VI). Significantly lower mean basic values of alpha-MSH and ACTH of light-haired persons in comparison with dark-haired and black persons (p less than 0,05) were demonstrated. We observed furthermore a significant increase of these proteo-hormones (alpha-MSH: skin type I: 26,7%, skin type II: 22,7%) in persons less pigmented within a short time after UV A whole-body irradiation in contrast to the more pigmented volunteers. These results prove a cutaneous peripheral sensor for UV A-rays, reacting with a different sensitivity depending on disposition and inducing endocrinological reactions. How this cutaneous-hypothalamic-pituitary stimulus mediation functions in detail is not completely revealed up to now. In what respect the present results, which can be explained as a consequence of evolutionary development, have a connection with the induction of melanoma remains to be seen.

Adrenocorticotropic Hormone↗

PubMed1984

[Effect of ultraviolet rays on alpha-MSH plasma concentration].

Influence of Ultraviolet Rays on alpha-MSH Plasmaconcentration. Ultraviolet total-body irradiation induces changes of alpha-MSH plasmaconcentration dependent on wave-length of the source of radiation as well as skin type of the volunteers. Following UV-A total-body irradiation, we observed a significant increase of the proteohormone alpha-MSH, whereas UV-B rays did not change the plasma concentration. With regard to persons showing skin type I or II, we found low alpha-MSH basic values which were significantly increased 1 hour after UV-A irradiation; in contrast, more pigmented volunteers (skin type III or VI) showed far higher basic values but only little increase after UV-A irradiation.

Adult↗

PubMed1984

[Malignant thymoma with polymorphic exanthema and erosive mucous membrane changes].

We report on a 30-year-old female patient with therapy-refractory polymorphous exanthema and widespread erosions in the oral and genital mucosa. The alterations demonstrated in the skin and genital mucosa were associated with a malignant thymoma with metastases being interpretatet as a paraneoplastic syndrome. There was a remarkably large spectrum of circulating antibodies, which had no corresponding clinical correlation. Our examination results indicate a dysregulation between cellular and humoral immunity, obviously caused by the malignant thymoma, with an extraordinary, uncontrolled production of antibodies against structures belonging to the body and alien structures.

Adult↗

PubMed1983

[Proliferative myositis].

A 86-year-old female patient is reported with myositis proliferans according to the criteria described by Enzinger and Dulcey (1967). This disease, first described by Kern (1960), impressed as a painful, firm and immovable tumor of almost 3 cm in size situated at the upper lip of our patient. Myositis proliferans can simulate a sarcoma, histologically and clinically; therefore, this disease shall be introduced to the dermatologic literature avoiding unnecessary invasive treatment. There is a relationship to fasciitis nodularis; a clinical and histological differentiation is possible as in our patient.

Aged↗