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R N Heasley

Publications and source records attributed to R N Heasley.

8 recordsLinked to original sources
PubMed1989

Short term outcome in babies refused perinatal intensive care.

OBJECTIVE: To compare the mortality in babies refused admission to a regional perinatal centre with that in babies accepted for intensive care in the centre. DESIGN: Retrospective study with group comparison. SETTING: Based at the Royal Maternity Hospital, Belfast, with follow up of patients in all obstetric units in Northern Ireland. PATIENTS: Requests for transfer of 675 babies to the regional perinatal centre (prenatally and postnatally) were made from hospitals in Northern Ireland between January 1984 and December 1986. In all, 343 babies were refused admission to the centre, and complete data were available for 332 of them. These babies were either admitted to other neonatal intensive care units (261 babies) or remained in hospitals with only special care cots (71 babies). MAIN OUTCOME MEASURE: Short term mortality. RESULTS: Seventy of the 332 babies refused admission to the centre died compared with 51 of the 333 who were admitted. Multivariate analysis based on a logistic model showed a non-significant increase in mortality among babies treated in other intensive care units compared with babies treated in the centre (relative odds 1.2; 95% confidence interval 0.7 to 1.9). The increase in mortality in babies who remained in a special care baby unit, however, was significant (3.5; 1.7 to 7.0). This increase was particularly significant in babies born at less than or equal to 32 weeks' gestation and who weighed less than 1500 g (8.4; 2.5 to 28.1). CONCLUSIONS: The results of the study confirm the benefits of neonatal intensive care and its particular value in improving survival in babies of low birth weight. As the babies were refused admission to the regional perinatal centre because intensive care cots were not available this deficiency should be corrected.

Gestational Age↗
PubMed1987

LHRH analogue therapy in infertile women with luteal phase defects.

Management of patients with unexplained (ovulatory) infertility is a difficult clinical problem. Some of these women exhibit repetitive luteal phase defects which may or may not respond to conventional treatment with anti-oestrogens or progesterone supplementation. Ablation of the defective cycles, by rendering the patients hypogonadotrophic, and then substituting induced cycles using exogenous gonadotrophins, was employed in 10 women who had been inexplicably infertile for up to 14 years. Over a trial period of six cycles good luteal phase progesterone profiles were achieved in all instances, but only two term pregnancies occurred. A further two patients conceived but one aborted and one had a tubal pregnancy. The results are discussed critically, regarding the importance of luteal phase defects in the aetiology of infertility and the conception rates which may occur even if no specific therapy is prescribed.

Adult↗