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Biomedical subjects

R N Sener

Publications and source records attributed to R N Sener.

At least 19 recordsLinked to original sources

Case report 717. Osteodysplasty (Melnick-Needles syndrome).

Herein reported is a patient with the typical osseous features of osteodysplasty, Melnick-Needles type, except for changes in the hands. Shortening of the distal phalanges is one of the reported features of this syndrome, while elongated phalanges are characteristic of frontometaphyseal dysplasia. The elongated proximal and middle phalanges of the hands in our case are similar to those changes found in frontometaphyseal dysplasia, suggesting some similarity in these two disorders. However, it must be remembered that other radiological features described in the text establish the entity of Melnick-Needles syndrome.

Bone and Bones

CT of gyriform calcification in tuberous sclerosis.

This paper presents a patient with typical clinical and CT features of tuberous sclerosis associated with gyriform calcification of the most part of the left frontal lobe. This patient represents the third case of tuberous sclerosis in the literature presenting with gyriform calcification.

Brain Diseases

Value of acute-phase angiography in the detection of vascular injuries caused by gunshot wounds to the head: analysis of 12 cases.

A study of the angiographic findings in consecutive civilian patients with cranial gunshot wounds examined in the acute stage has not been done. Most prior clinical studies have evaluated the findings in survivors in the subacute or chronic stages and have often been of war-time casualties. We determined the clinicoradiologic features of six cases of posttraumatic intracranial aneurysm, vascular occlusion, or arteriovenous fistula caused by penetrating missiles among 12 civilian patients who were examined in the acute posttraumatic stage (within 48 hr of injury) during a 1-year period. Three internal carotid/vertebral artery aneurysms, one external carotid artery aneurysm, one combined aneurysm/arteriovenous fistula of the vertebrobasilar circulation, and one cerebral venous occlusion were identified. The 50% overall prevalence of major vascular lesions in this series of civilian patients with penetrating missile injuries examined in the acute stage suggests these injuries are more common than previously suspected. It may indicate that selective cerebral angiography should be considered in the evaluation of the cranial vascular system of such persons.

Cerebral Angiography

Spondylolysis, spondylolisthesis, and associated nerve root entrapment in the lumbosacral spine: MR evaluation.

Spondylolysis is defined as a bone defect in the pars interarticularis. Its cause is uncertain but is believed in most cases to be related to repeated stress, trauma, or both. Findings of spondylolysis on conventional radiographs and on CT scans have been well characterized. Although these imaging techniques remain effective for the diagnosis of this defect, MR imaging is increasingly used as the primary or sole imaging method in patients with lower back pain and radiculopathy. Therefore, because MR images of the lumbar spine may be interpreted in the absence of correlative CT scans or conventional radiographs, the MR features of spondylolysis and its associated findings must be recognized. This essay illustrates the MR findings of lumbosacral spondylolysis and associated entrapment and direct impingement of the spinal nerve root.

Humans

The characteristics of cerebral meningiomas and surrounding tissues on dynamic CT.

Dynamic CT was utilized to evaluate 11 patients with histologically benign meningiomas. While it was found that all demonstrated macroscopic neovascularity, subtle differences in the dynamic perfusion curves were identified both between different meningiomas and from region to region within the same tumor. Other than basic anatomic differences, these changes may reflect intratumoral ischemia and hypothetically herald cystic/necrotic alteration within the neoplasm. The dynamic calculations over the surrounding brain showed areas of gross hyper- and hypoperfused cerebral cortex, and hypoperfused white matter in regions of peritumoral edema. These latter findings are of uncertain clinical importance. The dynamic examination also confirmed cases of dural venous sinus invasion and calvarial permeation by tumor. In addition, the dynamic series showed macroscopic neovascularity in one case with a completely negative selective cerebral arteriogram. It is felt that certain cases which have previously been evaluated by static CT may benefit from further study utilizing the dynamic method.

Adult

Retroperitoneal part of the femoral nerve. Normal ultrasound features.

The retroperitoneal part of the normal femoral nerve has been studied in 34 healthy subjects with ultrasound (US) to evaluate its course, thickness and anteroposterior diameter. A correlative cadaver study was also undertaken; a cadaver was scanned during dissection, and 12 cadavers were studied macroscopically to evaluate the length of the retroperitoneal part of the nerve. Because the femoral nerve could be well seen in its course in the retroperitoneum with US, it is suggested in this study which--to the authors' knowledge--is the first report on imaging of the femoral nerve, that sonography may serve as an initial imaging tool to detect lesions of the nerve itself as well as lesions adjacent to it.

Adolescent

Familial bilateral glomus jugulare tumors.

Glomus jugulare tumors may be bilateral or more commonly associated with a glomus tumor in another location. These tumors can also have a familial distribution which appears to be autosomal dominant. In this paper, two brothers are presented with bilateral glomus jugulare tumors. Such occurrence appears to be a unique familial manifestation.

Adult