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Biomedical subjects

R N Shaffer

Publications and source records attributed to R N Shaffer.

8 recordsLinked to original sources

Trabeculodialysis for inflammatory glaucoma: a review of 25 cases.

We reviewed the results following trabeculodialysis in 25 eyes of 22 patients with secondary glaucoma due to chronic anterior uveitis. After 1 year, intraocular pressure (IOP) was uncontrolled (greater than 21 mm Hg) in 11 eyes (44%). Trabeculodialysis controlled IOP (less than 21 mm Hg) in 14 eyes (56%), with an average follow up of 52 months (range, 12 to 151 months). Sixteen eyes (64%) were aphakic, but did no worse than the phakic eyes. One eye developed a subchoroidal hemorrhage 3 days postoperatively which required drainage. No other serious complications were encountered. Trabeculodialysis is a safe procedure which can achieve pressure control in these difficult eyes.

Aphakia

Analysis of surgical and medical management of glaucoma in Sturge-Weber syndrome.

Management of glaucoma associated with Sturge-Weber syndrome (SWS) is difficult. The authors reviewed 36 eyes of 30 SWS patients with either early or late-onset glaucoma with a mean follow-up of 122 months (range, 24-253 months). Intervals between required surgical or medical interventions were analyzed. Intervention was attributed to elevated intraocular pressure (IOP) in 55% of cases and disc change in 45%. Median stable postoperative interval with goniotomy was 12 months; with trabeculotomy, 21 months; with trabeculectomy, 34 months; with argon laser trabeculoplasty, 25 months; and with medications, 57 months. Survival analysis shows statistically significant differences between goniotomy and medications. Intraoperative choroidal expansions developed in 24% of cases receiving a trabeculectomy, and none developed with either goniotomy or trabeculotomy.

Adolescent

Adverse effects experienced by patients taking timolol.

Adverse effects involving one or more organ systems occurred in 38 of 165 patients with various types of glaucoma when timolol was added to their glaucoma therapy. It was necessary to discontinue timolol because of these side effects in 15 (9%) of the patients. Double-masked studies will be necessary to clarify the relationship of these adverse effects to the use of timolol.

Aged

Ciliary block (malignant) glaucoma.

A review of the history, recognition, mechanisms, and therapy of ciliary block glaucoma has been given. Cycloplegic therapy is stressed in the susceptible eye.

Choroid

Revision of filtration surgery.

Forty-one procedures were performed to revise malfunctioning filtering blebs in 37 eyes. Thirty-two procedures were undertaken on underfiltering blebs, seven on overfiltering blebs, and two on normally functioning but otherwise unsatisfactory blebs. Revision procedures were successful in 24 of 32 underfiltering blebs, four of seven overfiltering blebs, and one of two normally functioning but unsatisfactory blebs.

Adult

Fifty years in ophthalmology.

This renowned glaucoma expert began his residency just as gonioscopy came into existence, to be followed shortly by tonography. In this memoir, Dr. Shaffer shares anecdotes and insights gained over a half century of ophthalmology practice.

Glaucoma

Operative complications of goniotomy.

During 320 anesthesias, 401 goniotomies were performed and are here reviewed. Significant complications were cardiopulmonary arrest (1.8%) and postoperative hemorrhage (0.5%). Useful vision was lost in one case (0.2%). No complications could be attributed to operating on both eyes during the same anesthesia. The authors believe that both eyes should be operated on during the same anesthesia when bilateral goniotomy is indicated.

Glaucoma