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R Naclerio

Publications and source records attributed to R Naclerio.

24 records · Page 2Linked to original sources
PubMed1987

Endoscopic middle meatal antrostomy: theory, technique, and patency.

Ostial obstruction is a major factor in the pathogenesis of sinusitis. Detailed diagnostic evaluation in patients with maxillary sinusitis demonstrates the prominence of disease in the ethmoidal infundibulum and in adjacent ethmoid cells. Surgical procedures performed to improve maxillary sinusitis by inferior meatal antrostomy leave residual disease in the ostiomeatal area and may result in persistent mucociliary obstruction. Historically, the possibility of closure following ostial manipulation and the importance of dependent drainage of the maxillary sinus have been cited as arguments against the middle meatal approach. In this study of middle meatal antrostomies the patency rate was 98% between 4 and 32 months. The postoperative endoscopic findings and symptomatic improvement suggest that mucociliary clearance occurs through the surgically widened ostium. We conclude that endoscopic middle meatal antrostomy does not lead to ostial stenosis.

Adolescent↗
PubMed1983

Immunologic observations during desensitization and maintenance of clinical tolerance to penicillin.

A nurse anesthetist who had experienced four systemic allergic reactions attributed to penicillin exposure was safely and successfully desensitized to penicillin despite predominantly minor determinant allergy (benzyl penicilloate skin test was positive at 1:100,000 dilution of standard 10 mM solution). Because of unavoidable occupational exposure to penicillin, daily oral doses of penicillin were continued after hospital discharge in an effort to maintain clinical tolerance. Immunologic measurements throughout the long-term desensitization effort provided some evidence that in this patient, drug-induced mast cell desensitization is an ongoing dynamic process that is dose dependent and that skin mast cell reactivity recovers slowly over a period of many weeks after the short-term high-dose desensitization protocol. A dose-dependent state of clinical tolerance to inadvertent penicillin exposure has been safely maintained in this patient for 18 mo.

Desensitization, Immunologic↗
PubMed1981

A retrospective analysis of the intact canal wall tympanoplasty with mastoidectomy.

A retrospective analysis of patients who underwent surgery for chronic otitis media, cholesterol granuloma, and cholesteatoma between 1971 and 1979 was performed. The prevalence of postoperative cholesteatoma was higher than that previously reported in the literature. This emphasizes the need to re-explore patients who have had intact canal wall tympanoplasty with mastoidectomy performed for the removal of cholesteatoma. The elimination of cavity problems and better functional results must be balanced against the need for a second operation when an intact canal wall procedure for cholesteatoma is considered. Cholesteatomas occurring in children appear to be more aggressive than those occurring in adults.

Adolescent↗