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Biomedical subjects

R Noce

Publications and source records attributed to R Noce.

17 recordsLinked to original sources

Acute generalized exanthematic pustulosis (AGEP) in a patient treated with furosemide.

BACKGROUND: Although they appear more rarely than electrolyte disturbances, cutaneous reactions are important adverse effects of furosemide. This is particularly true for bullous skin eruptions, because they may be life-threatening. CASE REPORT: We describe a patient who developed acute generalized exanthematic pustulosis (AGEP) during treatment with furosemide. Because the patient had developed similar skin eruptions during treatment with furosemide years before, furosemide was considered the most likely cause of this reaction. The short period of time between exposure to furosemide and the appearance of the skin reaction, as well as a positive lymphocyte transformation test, suggest an immunological mechanism of the skin disease. CONCLUSION: AGEP is a possible cutaneous side effect of furosemide.

Aged↗

Our experience in pancreatic trauma.

The authors, with this works, call fellow members attention, how is complicate the diagnosis and the following surgical treatment of the associated lesions caused by pancreatic trauma. The pancreatic traumas are today object of discussion for the surgical treatment, and for the lesions associated. In this work is described the experience of some years accumulated in the Emergency Department of the Liguria Region.

Adolescent↗

[Trauma: when the liver "ruptures".... Our experience of 125 cases].

Liver and spleen are the organs most frequently involved in the blunt abdominal trauma. Prognosis is severe in those cases classified as IV or V according to the More score. The imaging techniques, particularly CT scan, offer today a possibility in the nonoperative management of a selected group of haemodynamically stable patients, therefore reducing the need of surgery. The authors' experience in 125 patients observed from 1983 to 1991 is reported.

Emergencies↗

Surgery and chemotherapy for pulmonary metastases: long-term results from a combined modality approach.

Eighty-three patients underwent pulmonary metastatectomy as part of a combined modality approach between 1. 1. 1972 and 31. 12. 1988 and 80 were followed up until 1. 1. 1990 or until death, with an average follow-up of 110 months. The estimated 5-, 10-, and 15-year survival rate was 38%, 32%, and 22% respectively. Recurrent pulmonary metastases were observed in 60% of the patients during follow-up with an estimated 24 months relapse-free survival rate of 50%. An additional 20% of the patients developed extrapulmonary recurrent tumor manifestation without evidence of pulmonary disease. One of five patients remained tumor free up to 207 months (an average of 87 months) after the initial pulmonary metastatectomy. A multivariate analysis identified completeness of tumor removal, the type of primary tumor, and a difference in histology between primary and metastatic neoplasm as three independent prognostic factors with significant impact on overall survival, the completeness of tumor removal being the most important one. Disease-free long-term survival for patients with pulmonary metastases treated by surgery and chemotherapy is related to completeness of tumor removal and the type of primary tumor.

Combined Modality Therapy↗

[Choledochal calculosis due to a suture thread].

The authors recently observed a patient suffering from recurrent choledochal, postcholecystectomy calculosis caused by suture thread. Given the relative rarity of this pathology, the difficulty of preoperative diagnosis and the possible confusion with other anatomoclinical syndromes, they take this opportunity to make a number of diagnostic and therapeutic comments in the light of the latest literature on this subject.

Cholecystectomy↗