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Biomedical subjects

R Nyberg

Publications and source records attributed to R Nyberg.

10 recordsLinked to original sources

Arthroscopic shoulder stabilization using transglenoid sutures.

The results of arthroscopic stabilization using multiple transglenoid sutures in 24 patients with posttraumatic recurrent anterior shoulder instability are presented with a minimum follow-up of 2 years. No serious complications were recorded. There were 2 recurrences. The remaining 22 patients had good or excellent results according to the modified Rowe score, with a median score of 89. The median value for loss of external rotation was 5 degrees. Seventeen patients were active in sports and 11 returned to the same sports at the same competitive level.

Adolescent↗

Quantitative analysis of surface and percutaneous electromyographic activity in lumbar erector spinae of normal young women.

Bilateral surface and fine-wire electromyographic activity from the erector spinae at the L4-5 interspace was recorded from 10 female subjects during flexion, extension, rotation to right/left, and sidebending to right/left. Fine-wire electrodes demonstrated significant left-right electromyographic differences during terminal flexion. Surface and fine-wire electromyographic recordings demonstrated a symmetric pattern of activity during extension. A symmetric pattern of erector spinae activity was observed during rotation using fine-wire electrodes but not from surface electrodes. Increased electromyographic activity from the contralateral erector spinae was detected by the surface electrodes during sidebending to neutral movements.

Adult↗

Lisinopril: dose-peak effect relationship in essential hypertension.

1. The dose-peak effect relationship of lisinopril was evaluated in a double-blind, parallel study in 83 patients with mild to moderate essential hypertension (supine diastolic blood pressure = 95-115 mm Hg). 2. After a 4 week placebo washout, patients were randomly assigned to one of four treatments: lisinopril 2.5, 10, 20 or 80 mg day-1 for 1 week. 3. Lisinopril 10 and 20 mg day-1 produced similar peak antihypertensive effects which were greater than that produced by 2.5 mg day-1, but less than that of 80 mg day-1. If the incidence of first-dose symptomatic hypotension is related to the peak effect, then an initial lisinopril dose of 20 mg should not pose any greater risk than a 10 mg dose. 4. The magnitude of antihypertensive response at 24 h postdrug appeared to be dose related across the 2.5 to 80 mg day-1 range.

Adult↗

Therapist agreement for palpation and observation of iliac crest heights.

Ten subjects were assessed by 11 examiners (three physical therapy students, three physical therapists experienced in rehabilitation, and five physical therapists experienced in orthopedics) to determine intrarater and interrater agreement for an assessment procedure involving palpation and observation of iliac crest heights. The results of two separate trials in a single session showed that both groups of experienced physical therapists had slightly higher intrarater and interrater agreement than student physical therapists. Findings suggest that a need exists to improve the reliability of this commonly used physical therapy assessment procedure.

Adipose Tissue↗

Vaginal administration of 15-methyl-PGF2 alpha-methyl ester prior to vacuum aspiration. Peri- and postoperative complications.

In order to simplify the operative technique and lower the postoperative complication rate, 354 healthy primigravidae were treated with a vaginal suppository containing 1 mg of 15-methyl-prostaglandin F2 alpha 12 hours prior to vacuum aspiration abortion in the first trimester. The mean cervical diameter found at the operation was 8.5 mm and in 38% of the women no further mechanical dilatation of the cervix was needed. The amount of bleeding during the operation was low (mean 30 ml, max. 300 ml). No perforations of the uterus or cervical lacerations occurred at operation. Side effects of the prostaglandin such as vomiting, diarrhea and lower abdominal pain occurred in 80% of the women and must be regarded as disturbing to the patient and seem to require that the women be hospitalized. The incidence of genital infection following the abortion was found to be 6.2%. In 8.2% of the women, the postoperative bleeding persisted for more than 14 days. It is concluded that if the frequency of side effects can be lowered by using new analogues of prostaglandins, pretreatment with vaginal suppositories may be recommended before vacuum-aspiration at legal abortion in the first trimester.

Abortion, Induced↗

Intraamniotic and intramuscular administration of 15-methyl prostaglandin F 2alpha for midtrimester abortion.

Two series of midtrimester abortion inductions are compared. In one series of 68 cases of midtrimester pregnancies (12-24 weeks), legal abortion was induced by one intraamniotic injection of 2.5 mg 15-methyl prostaglandin F 2alpha. Fetus was expelled in 67 cases (98.5%) after a mean time of 18.4 hours. One case with duplex failed to abort (1.5%). Abortion was complete in 54% of the aborted cases. In the second series of 93 cases abortion was induced by intramuscular injection of 300 microgram 15-methyl PGF 2alpha every third hour (the first dose was 200 microgram) during 30 hours. Fetus was expelled in 79 cases (85%) after a mean time of 16.7 hours. Failure occurred in 14 cases (15%). Abortion was complete in 57% of the aborted cases. Side effects (vomiting and diarrhea) were more frequent in the intramuscular series and very inconvenient to many of the patients. Excessive bleeding occurred more often in the intraamniotic series. A small rupture of the cervix was noted once (primigravida) in the intramuscular group. It is concluded that the intramuscular way of administration is a simple method of second trimester pregnancy termination with small bleedings but that otherwise it is inferior to the intraamniotic route.

Abortion, Induced↗

Intraamniotic administration of prostaglandin F2alpha for therapeutic abortion.

The present study was made to evaluate the efficiency of intraamiotically administered prostaglandin F2alpha upon unselected consecutive patients, hospitalized for legal abortion after the 12th week of pregnancy. In the first series, 178 cases were studied and in these the initial dose was related to the size of the uterus, i. e. 25 mg at 13 weeks, up to 40 mg at 24 weeks. A repeat injection of the same dose was required in 21% of the cases. Abortion occurred in 53% within 24 hours and in 81% within 48 hours. The mean abortion time was 32.3 hours. No failures occurred. In the second series, 73 patients were given an initial standardized dose of 40 mg irrespective of the size of the uterus. A repeat injection of 40 mg was given in 11%. Abortion occurred in 67% of the cases within 24 hours and in 80% within 48 hours. Four cases (5%) were failures. The mean time until expulsion of the fetus was 24.3 hours. Side effects in the form of vomiting and/or diarrhoea occurred about 2 times per patient in both series. In 20-30% a blood loss was sustained of more than 500 ml. Rupture of the cervix occurred in 3 cases. In both series multigravidae aborted faster than primigravidae. Early rupture of the membranes before the cervix was effaced caused very long abortion times in several cases.

Abortion, Therapeutic↗