PubMed Health⌕ Search

Biomedical subjects

R O Brandenburg

Publications and source records attributed to R O Brandenburg.

16 recordsLinked to original sources
PubMed1990

Monorail Piccolino catheter: a new rapid exchange/ultralow profile coronary angioplasty system.

The Monorail Piccolino coronary angioplasty balloon catheter (MBC) was evaluated on 118 patients at two centers. Technical success was achieved in 110 patients (93%). Time for catheter exchange and total fluoroscopy time were significantly lower for the Monorail catheter than with standard equipment (exchange time 97 vs. 170 seconds P less than .05 and fluoroscopy time 17 vs. 88 seconds P less than .001). The advantages of rapid exchange and the ability of utilize 2 Monorail balloon catheters through one 9F guiding catheter for simultaneous inflations allowed for maximal flexibility in treating patients with bifurcation lesions. The double wire approach utilizing one Monorail balloon catheter with a 7F guiding catheter was also technically successful. The Monorail Piccolino balloon catheter has unique features that allow for greater ease of operator use, rapid catheter exchange, and optimal angiographic visualization. It is felt that this catheter design provides distinct advantages over standard angioplasty equipment.

Angiography↗
PubMed1987

Raymond Pruitt.

Explore the source record for details and available documents.

Cardiology↗
PubMed1987

Jesse Edwards.

Explore the source record for details and available documents.

Cardiology↗
PubMed1985

Cardiomyopathies and their role in sudden death.

Frequent ventricular premature complexes, complex ventricular ectopic activity and asymptomatic ventricular tachycardia are common to both hypertrophic and dilated cardiomyopathy; in both conditions, sudden death is a common occurrence. Asymptomatic young patients with hypertrophic cardiomyopathy who have a family history and a high incidence of ventricular arrhythmias have a particularly high incidence of sudden death. In patients with hypertrophic cardiomyopathy, efforts to attribute sudden death to the cardiac index, left ventricular end-diastolic pressure, left ventricular outflow obstruction, ejection fraction, age, symptomatic state and septal thickness have been unrewarding. Myocardial hypertrophy and disordered myocardial cell arrangement are the likely substrates for the development of ventricular arrhythmias in hypertrophic cardiomyopathy. Ventricular fibrillation preceded by ventricular tachycardia appears to be the terminal event in most patients who die suddenly. In some patients, cardiac asystole is the terminal event. Additional factors playing a role in the development of the substrate for sudden death in patients with hypertrophic cardiomyopathy vary in importance on an individual basis. These factors include narrowing of septal arteries and the artery to the atrioventricular node, preservation of fetal anatomy with dispersion in the atrioventricular node and His bundle, fibrosis of the sinus node, clefts in the septum, multiple atrioventricular pathways and massive myocardial infarction. Patients with dilated cardiomyopathy appear to have the highest incidence of ventricular arrhythmias of any disease yet studied. The substrate for the development of ventricular arrhythmias in these patients appears to be myocardial hypertrophy and myocardial fibrosis.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1979

Ebstein's anomaly: the clinical features and natural history of Ebstein's anomaly of the tricuspid valve.

The clinical features and natural history of Ebstein's anomaly are analyzed on the basis of experience with 67 consecutive patients who have had a mean follow-up of 12 years. Of the total group, 26 (39%) of the patients remained in functional Class I or II and 41 (61%) progressed at some time into Class III or IV. Death occurred in 14 (21%) of the patients, and these were characterized by one or more of the following features: (1) they were in functional Class III or IV, (2) they had moderate to severe cardiomegaly with a cardiothoracic ratio greater than 0.65, (3) they had cyanosis or an arterial oxygen saturation of less than 90%, and (4) they were infants when the diagnosis was made (10 patients, of whom 5 died). In patients in Class III or IV, a comparison was made between patients treated medically (10) and those treated surgically--either with tricuspid valve replacement (15) or with a modified tricuspid annuloplasty (16). It appears that modified tricuspid annuloplasty is the procedure of choice, because despite an operative mortality of 25% (4 patients), 12 of the 16 patients so treated improved clinically or had a reduction in heart size.

Adolescent↗
PubMed1975

Aorta-coronary artery saphenous vein bypass grafts. Isolated and combined with other procedures.

The results in 578 patients who underwent a saphenous vein bypass graft operation (isolated SVBG) or a SVBG combined with other procedures (combined SVBG) from 1969 through 1972 were analyzed. The operative mortality rate was low (3 percent) for isolated SVBG but increased considerably for combined SVBG. The late mortality rate was also low (4 percent) for isolated SVBG and also increased markedly for combined SVBG. The operative mortality rate did not change in the group undergoing left ventricular aneurysmectomy or mitral valve surgery for postinfarction mitral insufficiency, whether or not SVBG was used; however, late results were better in both groups when SVBG was performed. Among all groups, patients with postinfarction mitral insufficiency or rheumatic mitral incompetence associated with coronary artery disease had the poorest outcome. Despite the operative and late deaths, patients undergoing SVBG with aortic valve replacement showed excellent results in the group of survivors.

Angina Pectoris↗