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Biomedical subjects

R P Carter

Publications and source records attributed to R P Carter.

9 recordsLinked to original sources
PubMed1981

The carbon dioxide laser in cervical intraepithelial neoplasia: a five-year experience in treating 230 patients.

Two hundred and thirty patients with cervical intraepithelial neoplasia were treated over a 5-year period with the carbon dioxide laser at the University of Kansas. Analysis of cytologic findings, biopsy results, location of the lesion, treatment factors, and recurrence rates are reported. Ninety percent of the patients were cytologically free of intraepithelial neoplasia at the end of the study.

Carbon Dioxide↗
PubMed1976

Prevention of bony fluorosis in aluminum smelter workers. A five-year study of fluoride absorption and excretion -- Pt. 3.

1. A study of over 52,000 urinary fluoride determinations collected over a 5-year period among aluminum smelter workers is described. The pre-shift urinary fluoride concentration (representative of bony burden) appears to increase less rapidly than the post-shift concentration. This slow rate of bony buildup of pre-shift urinary fluoride concentrations reflects the relatively slow uptake of fluoride by osseous tissues at these levels of exposure. 2. The utility of post-shift urinary fluoride analysis is reflected by its close correlation with improvement or deterioration in work practices which determines the degree of potential fluoride exposure. 3. Over 16,000 urinary tests for protein were performed in aluminum smelter workers. The absence of correlation between urinary fluoride concentrations and the presence of albuminuria indicates the absence of renal alteration among these workers.

Aluminum↗
PubMed1975

Fetal protection against masculinization with hyperreactio luteinalis and virilization.

In a unique patient with secondary amenorrhea and hirsutism prior to pregnancy, lutein cysts with hyperreactio luteinalis enlarged the ovaries to a diameter of 25 cm during pregnancy. The purpose of the study was to explore the possibility that placental aromatization of androgens may be a metabolic barrier that offers protection against masculinization of a female fetus. Maternal serum, umbilical cord serum and lutein cyst fluid were analyzed for testosterone, progesterone and estradiol content. The cardinal clinical findings were marked maternal virilization but no fetal masculinization. At the time of delivery, massive ovarian production of testosterone and a large maternal-fetal testosterone gradient were found. The maternal arm vein testosterone level, 15,000 ng/dl, was about 100 times normal level, the material ovarian vein level was 51,800 ng/dl, while the cord blood level was only 465 ng/dl. At the same time there was an increase in fetal cord blood estradiol to 33 ng/ml, a 7-fold increase compared to normal cord levels. A protective mechanism for the fetus may exist when maternal androgens are markedly elevated due to a maternal endocrinopathy concurrent with pregnancy. Our data are compatible with the concept that placental aromatization of androgens may function as a metabolic barrier, thus offering protection to the fetus from excessive maternal androgens. Another facet of the protective mechanism may be increased fetal exposure to potent estrogens, which may buffer the influence of androgens reaching the fetus.

Adult↗
PubMed1969

High labial.

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Orthodontic Appliances↗