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Biomedical subjects

R P Kaplan

Publications and source records attributed to R P Kaplan.

9 recordsLinked to original sources

Drug-induced pemphigus related to angiotensin-converting enzyme inhibitors.

We report a case of drug-induced pemphigus caused by an angiotensin-converting enzyme inhibitor, captopril. The cutaneous reaction remitted after withdrawal of captopril therapy. Unique to this case, however, was the substitution of another angiotensin-converting enzyme inhibitor, enalapril, without exacerbation of the pemphigus. To the best of our knowledge, this is the first reported patient with captopril-induced pemphigus in whom no new lesions developed after subsequent treatment with enalapril. A difference in chemical structure between these two drugs, particularly of a sulfur moiety, may help explain why the drug-induced disease did not recur.

Aged

Sweet syndrome in a neonate with aseptic meningitis.

A 7-week-old infant with antecedent otitis media, upper respiratory infection, and aseptic meningitis was diagnosed as having Sweet syndrome. Although this disease usually affects adults, it has been reported in 17 children. This is the youngest reported patient with the disorder to date, and the first in whom the syndrome was associated with aseptic meningitis.

Humans

The aging skin.

Explore the source record for details and available documents.

Aged

Euthanasia legislation: a survey and a model act.

With increasing frequency, state legislators have been proposing legislation which would permit euthanasia--the allowance of "death with dignity" --under certain circumstances. These proposals indicate varying degrees of awareness of the issues and problems involved in drafting euthanasia legislation. The Article focuses on such issues and problems, studies the methods proposed by legislators to deal with them, and offers a Modle Euthanasia Act designed to achieve their optimal solution.

Euthanasia